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Michael Barber,  D.Phil.
Associate Dean for Graduate and Postdoctoral Affairs, College of Medicine - School of Biomedical Sciences
Director, Graduate Certificate in Health Sciences
Director, Graduate Certificate in Medical Biochemistry, Microbiology & Immunology
Director, Graduate Certificate in Molecular Medicine
Director, Graduate Certificate in Biotechnology
Director, Graduate Certificate in Bioinformatics
Director, Graduate Certificate in Biochemistry & Molecular Biology
Director, Masters Program in Biochemistry & Molecular Biology
Director, Masters Program in Bioinformatics & Computational Biology

Administrative Appointment: Assoc Dean
Primary Department: COLLEGE OF MEDICINE MOLECULAR MEDICINE

Assoc Dean & Dist Professor
COLLEGE OF MEDICINE MOLECULAR MEDICINE

Distinguished Professor
COP DEPT OF PHARMACEUTICAL SCIENCE

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Contacts
Email: mbarber@health.usf.edu
Phone: (813) 974-9908
Office: MDC, 1060
Mailing address 12901 Bruce B. Downs Blvd. MDC 40
Tampa, FL 33612
View My C. V.
 
Education
  • PHD, Biochemistry, University Of Sussex , Sussex, England - 1976.
  • M.Sc., Enzyme Chemistry, University of Kent, U.K. , Kent, United Kingdom - 1973.
  • B.Sc. Hons., Chemistry, University of Kent, U.K. , Kent, United Kingdom - 1972.
  •  
    Interdisciplinary & Emerging Signature Programs
    Cardiovascular.
     
    Research Summary

    My research focuses on how enzymes containing novel metal atoms or other non-protein components enhance biological activity.

     
    Links
    Personal Page:   http://health.usf.edu/medicine/graduatestudies/contact.htm
    Lab Link:  http://hscweb3.hsc.usf.edu/health/now/?p=233


    Selected Publications
  • Percy, MJ.Crowley, LJ.Roper, D.Vulliamy, TJ.Layton, DM.Barber, MJ. Identification and characterization of the novel FAD-binding lobe G75S mutation in cytochrome b(5) reductase: an aid to determine recessive congenital methemoglobinemia status in an infant. Blood cells, molecules & diseases. 36(1): 81-90, .
  • Percy, MJ.Crowley, LJ.Boudreaux, J.Barber, MJ. Expression of a novel P275L variant of NADH:cytochrome b5 reductase gives functional insight into the conserved motif important for pyridine nucleotide binding. Archives of biochemistry and biophysics. 447(1): 59-67, 2006.
  • Roma, GW.Crowley, LJ.Barber, MJ. Expression and characterization of a functional canine variant of cytochrome b5 reductase. Archives of biochemistry and biophysics. 452(1): 69-82, 2006.
  • Barber, MJ.Sampson, SN.Schneider, RK.Baszler, T.Tucker, RL. Use of magnetic resonance imaging to diagnose distal sesamoid bone injury in a horse. Journal of the American Veterinary Medical Association. 229(5): 717-20, 2006.
  • Marohnic, CC.Crowley, LJ.Davis, CA.Smith, ET.Barber, MJ. Cytochrome b5 reductase: role of the si-face residues, proline 92 and tyrosine 93, in structure and catalysis. Biochemistry. 44(7): 2449-61, 2005.
  • Roma, GW.Crowley, LJ.Davis, CA.Barber, MJ. Mutagenesis of Glycine 179 modulates both catalytic efficiency and reduced pyridine nucleotide specificity in cytochrome b5 reductase. Biochemistry. 44(41): 13467-76, 2005.
  • Percy, MJ.Crowley, LJ.Davis, CA.McMullin, MF.Savage, G.Hughes, J.McMahon, C.Quinn, RJ.Smith, O.Barber, MJ.Lappin, TR. Recessive congenital methaemoglobinaemia: functional characterization of the novel D239G mutation in the NADH-binding lobe of cytochrome b5 reductase. British journal of haematology. 129(6): 847-53, 2005.
  • Davis, CA.Crowley, LJ.Barber, MJ. Cytochrome b5 reductase: the roles of the recessive congenital methemoglobinemia mutants P144L, L148P, and R159*. Archives of biochemistry and biophysics. 431(2): 233-44, 2004.
  • Davis, CA.Barber, MJ. Cytochrome b5 oxidoreductase: expression and characterization of the original familial ideopathic methemoglobinemia mutations E255- and G291D. Archives of biochemistry and biophysics. 425(2): 123-32, 2004.
  • Pollock, VV.Conover, RC.Johnson, MK.Barber, MJ. Biotin sulfoxide reductase: Tryptophan 90 is required for efficient substrate utilization. Archives of biochemistry and biophysics. 409(2): 315-26, 2003.
  • Davis, CA.Barber, MJ. Heterologous expression of enzymopenic methemoglobinemia variants using a novel NADH:cytochrome c reductase fusion protein. Protein expression and purification. 30(1): 43-54, 2003.
  • Bewley, MC.Davis, CA.Marohnic, CC.Taormina, D.Barber, MJ. The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site. Biochemistry. 42(45): 13145-51, 2003.
  • Marohnic, CC.Bewley, MC.Barber, MJ. Engineering and characterization of a NADPH-utilizing cytochrome b5 reductase. Biochemistry. 42(38): 11170-82, 2003.
  • Smith, ET.Davis, CA.Barber, MJ. Voltammetric simulations of multiple electron transfer/proton transfer coupled reactions: flavin adenine dinucleotide as a model system. Analytical biochemistry. 323(1): 114-21, 2003.
  • Pollock, VV.Conover, RC.Johnson, MK.Barber, MJ. Bacterial expression of the molybdenum domain of assimilatory nitrate reductase: production of both the functional molybdenum-containing domain and the nonfunctional tungsten analog. Archives of biochemistry and biophysics. 403(2): 237-48, 2002.
  • Davis, CA.Dhawan, IK.Johnson, MK.Barber, MJ. Heterologous expression of an endogenous rat cytochrome b(5)/cytochrome b(5) reductase fusion protein: identification of histidines 62 and 85 as the heme axial ligands. Archives of biochemistry and biophysics. 400(1): 63-75, 2002.
  • Barber, MJ.Desai, SK.Marohnic, CC.Hernandez, HH.Pollock, VV. Synthesis and bacterial expression of a gene encoding the heme domain of assimilatory nitrate reductase. Archives of biochemistry and biophysics. 402(1): 38-50, 2002.
  • Pollock, VV.Barber, MJ. Kinetic and mechanistic properties of biotin sulfoxide reductase. Biochemistry. 40(5): 1430-40, 2001.
  • Cheltsov, AV.Barber, MJ.Ferreira, GC. Circular permutation of 5-aminolevulinate synthase. Mapping the polypeptide chain to its function. The Journal of biological chemistry. 276(22): 19141-9, 2001.
  • Bewley, MC.Marohnic, CC.Barber, MJ. The structure and biochemistry of NADH-dependent cytochrome b5 reductase are now consistent. Biochemistry. 40(45): 13574-82, 2001.
  • Franco, R.Pereira, AS.Tavares, P.Mangravita, A.Barber, MJ.Moura, I.Ferreira, GC. Substitution of murine ferrochelatase glutamate-287 with glutamine or alanine leads to porphyrin substrate-bound variants. The Biochemical journal. 356(Pt 1): 217-22, 2001.
  • Marohnic, CC.Barber, MJ. Arginine 91 is not essential for flavin incorporation in hepatic cytochrome b(5) reductase. Archives of biochemistry and biophysics. 389(2): 223-33, 2001.
  • Barber, MJ.Desai, SK.Marohnic, CC. Assimilatory nitrate reductase: lysine 741 participates in pyridine nucleotide binding via charge complementarity. Archives of biochemistry and biophysics. 394(1): 99-110, 2001.
  • Barber, MJ.Quinn, GB. Production of a recombinant hybrid hemoflavoprotein: engineering a functional NADH:cytochrome c reductase. Protein expression and purification. 23(2): 348-58, 2001.
  • Kim, TH.Zhao, Y.Barber, MJ.Kuharsky, DK.Yin, XM. Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax. The Journal of biological chemistry. 275(50): 39474-81, 2000.
  • Garton, SD.Temple, CA.Dhawan, IK.Barber, MJ.Rajagopalan, KV.Johnson, MK. Resonance Raman characterization of biotin sulfoxide reductase. Comparing oxomolybdenum enzymes in the ME(2)SO reductase family. The Journal of biological chemistry. 275(10): 6798-805, 2000.
  • Pollock, VV.Barber, MJ. Serine 121 is an essential amino acid for biotin sulfoxide reductase functionality. The Journal of biological chemistry. 275(45): 35086-90, 2000.
  • Kluck, RM.Esposti, MD.Perkins, G.Renken, C.Kuwana, T.Bossy-Wetzel, E.Goldberg, M.Allen, T.Barber, MJ.Green, DR.Newmeyer, DD. The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol. The Journal of cell biology. 147(4): 809-22, 1999.
  • Tan, D.Barber, MJ.Ferreira, GC. The role of tyrosine 121 in cofactor binding of 5-aminolevulinate synthase. Protein science : a publication of the Protein Society. 7(5): 1208-13, 1998.
  • Barber, MJ.Trimboli, AJ.Nomikos, S.Smith, ET. Direct electrochemistry of the flavin domain of assimilatory nitrate reductase: effects of NAD+ and NAD+ analogs. Archives of biochemistry and biophysics. 345(1): 88-96, 1997.
  • Pollock, VV.Barber, MJ. Biotin sulfoxide reductase. Heterologous expression and characterization of a functional molybdopterin guanine dinucleotide-containing enzyme. The Journal of biological chemistry. 272(6): 3355-62, 1997.
  • Quinn, GB.Trimboli, AJ.Prosser, IM.Barber, MJ. Spectroscopic and kinetic properties of a recombinant form of the flavin domain of spinach NADH: nitrate reductase. Archives of biochemistry and biophysics. 327(1): 151-60, 1996.
  • Trimboli, AJ.Quinn, GB.Smith, ET.Barber, MJ. Thiol modification and site directed mutagenesis of the flavin domain of spinach NADH:nitrate reductase. Archives of biochemistry and biophysics. 331(1): 117-26, 1996.
  • Barber, MJ.Quinn, GB. High-level expression in Escherichia coli of the soluble, catalytic domain of rat hepatic cytochrome b5 reductase. Protein expression and purification. 8(1): 41-7, 1996.
  • Gong, J.Kay, CJ.Barber, MJ.Ferreira, GC. Mutations at a glycine loop in aminolevulinate synthase affect pyridoxal phosphate cofactor binding and catalysis. Biochemistry. 35(45): 14109-17, 1996.
  • Barber, MJ.Kay, CJ. Superoxide production during reduction of molecular oxygen by assimilatory nitrate reductase. Archives of biochemistry and biophysics. 326(2): 227-32, 1996.
  • Barber, MJ.Van Valkenburgh, H.Trimboli, AJ.Pollock, VV.Neame, PJ.Bastian, NR. The amino acid sequence of Rhodobacter sphaeroides dimethyl sulfoxide reductase. Archives of biochemistry and biophysics. 320(2): 266-75, 1995.
  • Byvoet, P.Balis, JU.Shelley, SA.Montgomery, MR.Barber, MJ. Detection of hydroxyl radicals upon interaction of ozone with aqueous media or extracellular surfactant: the role of trace iron. Archives of biochemistry and biophysics. 319(2): 464-9, 1995.
  • Ferreira, GC.Vajapey, U.Hafez, O.Hunter, GA.Barber, MJ. Aminolevulinate synthase: lysine 313 is not essential for binding the pyridoxal phosphate cofactor but is essential for catalysis. Protein science : a publication of the Protein Society. 4(5): 1001-6, 1995.
  • Pollock, VV.Barber, MJ. Molecular cloning and expression of biotin sulfoxide reductase from Rhodobacter sphaeroides forma sp. denitrificans. Archives of biochemistry and biophysics. 318(2): 322-32, 1995.
  • Trimboli, AJ.Barber, MJ. Assimilatory nitrate reductase: reduction and inhibition by NADH/NAD+ analogs. Archives of biochemistry and biophysics. 315(1): 48-53, 1994.
  • Quinn, GB.Trimboli, AJ.Barber, MJ. Construction and expression of a flavocytochrome b5 chimera. The Journal of biological chemistry. 269(18): 13375-81, 1994.
  • Barber, MJ.Trimboli, AJ.McIntire, WS. The amino acid sequence of Pseudomonas putida azurin. Archives of biochemistry and biophysics. 303(1): 22-6, 1993.
  • Barber, MJ.Trimboli, AJ.Clark, M.Young, C.Neame, PJ. Purification and properties of Alligator mississipiensis cytochrome c. Archives of biochemistry and biophysics. 301(2): 294-8, 1993.
  • Cannons, AC.Barber, MJ.Solomonson, LP. Expression and characterization of the heme-binding domain of Chlorella nitrate reductase. The Journal of biological chemistry. 268(5): 3268-71, 1993.
  • Barber, MJ.Neame, PJ.Lim, LW.White, S.Matthews, FS. Correlation of x-ray deduced and experimental amino acid sequences of trimethylamine dehydrogenase. The Journal of biological chemistry. 267(10): 6611-9, 1992.
  • Kay, CJ.Solomonson, LP.Barber, MJ. Electrochemical and kinetic analysis of electron-transfer reactions of Chlorella nitrate reductase. Biochemistry. 30(48): 11445-50, 1991.
  • Bastian, NR.Kay, CJ.Barber, MJ.Rajagopalan, KV. Spectroscopic studies of the molybdenum-containing dimethyl sulfoxide reductase from Rhodobacter sphaeroides f. sp. denitrificans. The Journal of biological chemistry. 266(1): 45-51, 1991.
  • Kay, CJ.Barber, MJ.Solomonson, LP.Kau, D.Cannons, AC.Hipkin, CR. Spectroscopic, thermodynamic and kinetic properties of Candida nitratophila nitrate reductase. The Biochemical journal. 272(2): 545-8, 1990.
  • Barber, MJ.Notton, BA. Spinach Nitrate Reductase : Effects of Ionic Strength and pH on the Full and Partial Enzyme Activities. Plant physiology. 93(2): 537-540, 1990.
  • Kay, CJ.Barber, MJ. Measurement of oxidation-reduction midpoint potentials by room temperature electron paramagnetic resonance potentiometry. Analytical biochemistry. 184(1): 11-5, 1990.
  • Barber, MJ.Neame, PJ. A conserved cysteine in molybdenum oxotransferases. The Journal of biological chemistry. 265(34): 20912-5, 1990.
  • Kay, CJ.Solomonson, LP.Barber, MJ. Oxidation-reduction potentials of flavin and Mo-pterin centers in assimilatory nitrate reductase: variation with pH. Biochemistry. 29(48): 10823-8, 1990.
  • Kay, CJ.Barber, MJ.Notton, BA.Solomonson, LP. Oxidation--reduction midpoint potentials of the flavin, haem and Mo-pterin centres in spinach (Spinacia oleracea L.) nitrate reductase. The Biochemical journal. 263(1): 285-7, 1989.
  • Neame, PJ.Barber, MJ. Conserved domains in molybdenum hydroxylases. The amino acid sequence of chicken hepatic sulfite oxidase. The Journal of biological chemistry. 264(35): 20894-901, 1989.
  • Kay, CJ.Barber, MJ. EPR and kinetic analysis of the interaction of halides and phosphate with nitrate reductase. Biochemistry. 28(14): 5750-8, 1989.
  • Barber, MJ.Notton, BA.Kay, CJ.Solomonson, LP. Chloride Inhibition of Spinach Nitrate Reductase. Plant physiology. 90(1): 70-74, 1989.
  • Barber, MJ.Pollock, V.Spence, JT. Microcoulometric analysis of trimethylamine dehydrogenase. The Biochemical journal. 256(2): 657-9, 1988.
  • Kay, CJ.Barber, MJ.Solomonson, LP. Circular dichroism and potentiometry of FAD, heme and Mo-pterin prosthetic groups of assimilatory nitrate reductase. Biochemistry. 27(16): 6142-9, 1988.
  • Rosen, GM.Britigan, BE.Cohen, MS.Ellington, SP.Barber, MJ. Detection of phagocyte-derived free radicals with spin trapping techniques: effect of temperature and cellular metabolism. Biochimica et biophysica acta. 969(3): 236-41, 1988.
  • Spence, JT.Barber, MJ.Solomonson, LP. Stoichiometry of electron uptake and oxidation-reduction midpoint potentials of NADH:nitrate reductase. The Biochemical journal. 250(3): 921-3, 1988.
  • Terlesky, KC.Barber, MJ.Aceti, DJ.Ferry, JG. EPR properties of the Ni-Fe-C center in an enzyme complex with carbon monoxide dehydrogenase activity from acetate-grown Methanosarcina thermophila. Evidence that acetyl-CoA is a physiological substrate. The Journal of biological chemistry. 262(32): 15392-5, 1987.
  • Gardlik, S.Barber, MJ.Rajagopalan, KV. A molybdopterin-free form of xanthine oxidase. Archives of biochemistry and biophysics. 259(2): 363-71, 1987.
  • Eichler, DC.Solomonson, LP.Barber, MJ.McCreery, MJ.Ness, GC. Radiation inactivation analysis of enzymes. Effect of free radical scavengers on apparent target sizes. The Journal of biological chemistry. 262(20): 9433-6, 1987.
  • Barber, MJ.Eichler, DC.Solomonson, LP.Ackrell, BA. Anti-flavin antibodies. The Biochemical journal. 242(1): 89-95, 1987.
  • Barber, MJ.Notton, BA.Solomonson, LP. Oxidation-reduction midpoint potentials of the molybdenum center in spinach NADH:nitrate reductase. FEBS letters. 213(2): 372-4, 1987.
  • Solomonson, LP.McCreery, MJ.Kay, CJ.Barber, MJ. Radiation inactivation analysis of assimilatory NADH:nitrate reductase. Apparent functional sizes of partial activities associated with intact and proteolytically modified enzyme. The Journal of biological chemistry. 262(18): 8934-9, 1987.
  • Barber, MJ.Solomonson, LP.McCreery, MJ. Radiation inactivation of hepatic sulfite oxidase. Archives of biochemistry and biophysics. 256(1): 260-4, 1987.
  • Barber, MJ.Trudeau, W.Byvoet, P. Use of double spin-labeled histones to monitor histone-chromatin integration. Biochemical and biophysical research communications. 141(2): 434-9, 1986.
  • Kay, CJ.Solomonson, LP.Barber, MJ. Thermodynamic properties of the heme prosthetic group in assimilatory nitrate reductase. The Journal of biological chemistry. 261(13): 5799-802, 1986.
  • Solomonson, LP.Barber, MJ.Robbins, AP.Oaks, A. Functional domains of assimilatory NADH:nitrate reductase from Chlorella. The Journal of biological chemistry. 261(24): 11290-4, 1986.
  • Capeillère-Blandin, C.Barber, MJ.Bray, RC. Comparison of the processes involved in reduction by the substrate for two homologous flavocytochromes b2 from different species of yeast. The Biochemical journal. 238(3): 745-56, 1986.
  • Kay, CJ.Barber, MJ. Assimilatory nitrate reductase from Chlorella. Effect of ionic strength and pH on catalytic activity. The Journal of biological chemistry. 261(30): 14125-9, 1986.
  • Barber, MJ.Solomonson, LP. The role of the essential sulfhydryl group in assimilatory NADH: nitrate reductase of Chlorella. The Journal of biological chemistry. 261(10): 4562-7, 1986.
  • Barber, MJ.Solomonson, LP.Eichler, DC. Spin-labeled erythrocyte membranes: direct identification of nitroxide-conjugated proteins. Biochemical and biophysical research communications. 127(3): 793-8, 1985.
  • Eichler, DC.Barber, MJ.Solomonson, LP. Anti-nitroxide immunoglobulin G: analysis of antibody specificity and their application as probes for spin-labeled proteins. Biochemistry. 24(5): 1181-6, 1985.
  • Solomonson, LP.Barber, MJ. Spin-labeled ouabain as a probe for cardiac glycoside receptor/Na, K-ATPase. Biochemical and biophysical research communications. 124(1): 210-6, 1984.
  • Solomonson, LP.Barber, MJ.Howard, WD.Johnson, JL.Rajagopalan, KV. Electron paramagnetic resonance studies on the molybdenum center of assimilatory NADH:nitrate reductase from Chlorella vulgaris. The Journal of biological chemistry. 259(2): 849-53, 1984.
  • Coughlan, MP.Mehra, RK.Barber, MJ.Siegel, LM. Optical and electron paramagnetic resonance spectroscopic studies on purine hydroxylase II from Aspergillus nidulans. Archives of biochemistry and biophysics. 229(2): 596-603, 1984.
  • Barber, MJ.Zektzer, AS.Rosen, GM.DĂ«mos, HA.Rauckman, EJ. Electron paramagnetic resonance studies of membrane proteins in hepatic microsomes. Biochimica et biophysica acta. 776(1): 159-68, 1984.
  • Barber, MJ.Siegel, LM. Electron paramagnetic resonance and potentiometric studies of arsenite interaction with the molybdenum centers of xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: a specific stabilization of the molybdenum(V) oxidation state. Biochemistry. 22(3): 618-24, 1983.
  • Rosen, GM.Barber, MJ.Rauckman, EJ. Disruption of erythrocyte membranal organization by superoxide. The Journal of biological chemistry. 258(4): 2225-8, 1983.
  • Barber, MJ.Rosen, GM.Siegel, LM.Rauckman, EJ. Evidence for formation of superoxide and formate radicals in Methanobacterium formicicum. Journal of bacteriology. 153(3): 1282-6, 1983.
  • Barber, MJ.Rosen, GM.Rauckman, EJ. Studies of the mobility of maleimide spin labels within the erythrocyte membrane. Biochimica et biophysica acta. 732(1): 126-32, 1983.
  • Janick, PA.Rueger, DC.Krueger, RJ.Barber, MJ.Siegel, LM. Characterization of complexes between Escherichia coli sulfite reductase hemoprotein subunit and its substrates sulfite and nitrite. Biochemistry. 22(2): 396-408, 1983.
  • Barber, MJ.Siegel, LM.Schauer, NL.May, HD.Ferry, JG. Formate dehydrogenase from Methanobacterium formicicum. Electron paramagnetic resonance spectroscopy of the molybdenum and iron-sulfur centers. The Journal of biological chemistry. 258(18): 10839-45, 1983.
  • Barber, MJ.Siegel, LM. Oxidation-reduction potentials of molybdenum, flavin, and iron-sulfur centers in milk xanthine oxidase: variation with pH. Biochemistry. 21(7): 1638-47, 1982.
  • Barber, MJ.Salerno, JC.Siegel, LM. Magnetic interactions in milk xanthine oxidase. Biochemistry. 21(7): 1648-56, 1982.
  • Spence, JT.Barber, MJ.Siegel, LM. Determination of the stoichiometry of electron uptake and the midpoint reduction potentials of milk xanthine oxidase at 25 degrees C by microcoulometry. Biochemistry. 21(7): 1656-61, 1982.
  • Barber, MJ.Coughlan, MP.Kanda, M.Rajagopalan, KV. Electron paramagnetic resonance properties and oxidation-reduction potentials of the molybdenum, flavin, and iron-sulfur centers of chicken liver xanthine dehydrogenase. Archives of biochemistry and biophysics. 201(2): 468-75, 1980.
  • Bray, RC.Barber, MJ.Lowe, DJ. Electron-paramagnetic-resonance spectroscopy of complexes of xanthine oxidase with xanthine and uric acid. The Biochemical journal. 171(3): 653-8, 1978.
  • Williams-Smith, DL.Bray, RC.Barber, MJ.Tsopanakis, AD.Vincent, SP. Changes in apparent pH on freezing aqueous buffer solutions and their relevance to biochemical electron-paramagnetic-resonance spectroscopy. The Biochemical journal. 167(3): 593-600, 1977.
  • Barber, MJ.Bray, RC.Cammack, R.Coughlan, MP. Oxidation--reduction potentials of turkey liver xanthine dehydrogenase and the origins of oxidase and dehydrogenase behaviour in molybdenum-containing hydroxylases. The Biochemical journal. 163(2): 279-89, 1977.
  • Cammack, R.Barber, MJ.Bray, RC. Oxidation-reduction potentials of molybdenum, flavin and iron-sulphur centres in milk xanthine oxidase. The Biochemical journal. 157(2): 469-78, 1976.
  • Barber, MJ.Bray, RC.Lowe, DJ.Coughlan, MP. Studies by electron-paramagnetic-resonance spectroscopy and stopped-flow spectrophotometry on the mechanism of action of turkey liver xanthine dehydrogenase. The Biochemical journal. 153(2): 297-307, 1976.
  • Lowe, DJ.Barber, MJ.Pawlik, RT.Bray, RC. A new non-functional form of milk xanthine oxidase containing stable quinquivalent molybdenum. The Biochemical journal. 155(1): 81-5, 1976.
  • Bray, RC.Barber, MJ.Dalton, H.Lowe, DJ.Coughlan, MP. Iron-sulphur systems in some isolated multi-component oxidative enzymes. Biochemical Society transactions. 3(4): 479-82, 1975.
  • Bray, RC.Lowe, DJ.Barber, MJ. Distribution of reducing equivalents on xanthine oxidase molecules and the rates of the intramolecular electron-transfer reactions. The Biochemical journal. 141(1): 309-11, 1974.

  • Positions Held
  • President (Faculty Council-College of Medicine, University of South Florida 2005 - 2006)
  • Chair (LCME College of Medicine Evaluation Committee I - Institutional Setting: Governance and Administration, University of South Florida 2005 - 2006)
  • Professor (Department of Biochemistry & Molecular Biology, College of Medicine, University of South Florida 1991 - 2006)
  • Member (AIMS Council-College of Medicine, University of South Florida 2005 - 2005)
  • Founding Member (Institute for Biomolecular Science, University of South Florida 1986 - 2002)
  • Associate Director (Institute for Biomolecular Science, University of South Florida 1994 - 1996)
  • Director (Interdisciplinary Ph.D. Program in Cellular & Molecular Biology, University of South Florida Institute for Biomolecular Science 1994 - 1996)
  • Associate Professor (Department of Biochemistry & Molecular Biology, College of Medicine, University of South Florida 1987 - 1991)
  • Assistant Professor (Department of Biochemistry, College of Medicine, University of South Florida 1983 - 1987)
  • Senior Research Associate (Department of Biochemistry, Medical School, Duke University 1981 - 1983)
  • Research Associate (Department of Biochemistry, Medical School, Duke University 1977 - 1981)
  • Lecturer (Department of Physical Sciences, Open University 1976 - 1977)
  • Predoctoral Fellow (School of Molecular Sciences, University of Sussex 1973 - 1977)


  • Memberships
  • Peer Review Committee 5C, Am. Heart Assoc., Florida/Puerto Rico Affiliate (Member, 2004 - 2007)
  • American Heart Assoc. Florida/Puerto Rico Affl. Hillsborough Community (Member, 2005 - 2006)


  • Awards/Honors
  • Commencement Marshal (University of South Florida - 2008)
  • Distinguished University Health Professor (University of South Florida, College of Medicine - 2007)
  • Graduate Education Award (Department of Molecular Medicine, University of South Florida, College of Medicine - 2007)
  • Grasso Award (Association of Medical Science Graduate Students, University of South Florida, College of Medicine - 2007)
  • Commencement Marshal (University of South Florida - 2007)
  • USF Health Distinguished Professor nomination (University of South Florida - 2007)
  • Fellow (USF Health Leadership Institute, University of South Florida, College of Medicine (Charter Class Mem - 2007)
  • University Distinguished Professor nomination (University of South Florida - 2006)
  • Whos Who Among Executives and Professionals ( - 2006)
  • Outstanding Achievement Award, Department of Molecular Medicine (University of South Florida, College of Medicine - 2006)
  • Commencement Marshal (University of South Florida - 2006)
  • Commencement Marshal (University of South Florida - 2005)
  • University Distinguished Professor nomination (University of South Florida - 2005)
  • Commencement Marshal (University of South Florida, College of Medcine - 2004)
  • Who's Who in Medical Sciences Education ( - 2004)
  • Who's Who in Sciences Higher Education ( - 2004)
  • Commencement Marshal (University of South Florida - 2003)
  • Service First Award (State of Florida - 2002)


  • Lectures
  • "Faculty Leadership Development" University of South Florida, College of Medicine. FL, United States - 2002.

  • Profile last modified on 02/05/2014