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Marcia Gordon,  Ph.D.
Professor, Department of Molecular Pharmacology and Physiology


Primary Department: COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

Professor
COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

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Contacts
Email: mgordon@health.usf.edu
Phone: (813) 974-9926
Office: ALZ, 443
Mailing address USF Health Byrd Alzheimer's Institute 4001 E. Fletcher Ave.
Tampa, FL 33613
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Education
  • PHD, Molecular Biology, University Of Southern California , Los Angeles, CA, United States - 1985.
  • B.S., Psychobiology, University of Southern California ,USA - 1978.
  •  
    Interdisciplinary & Emerging Signature Programs
    Cancer Biology, Cellular and Molecular Biology, Neurodegenerative Disease, Neuroscience, Neuroscience, Allergy, Immunology & Infectious Disease, Biomedical Engineering & Nanomedicine.
     
    Research Summary

    * Experimental therapeutics for Alzheimer's disease using animal models
    * Role of glial cells and neuroinflammation in neurodegeneration
    * Development of neuroprotective therapeutics

     


    Selected Publications
  • Brownlow, ML.Benner, L.D'Agostino, D.Gordon, MN.Morgan, D. Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology. PloS one. 8(9): e75713, 2013.
  • Selenica, ML.Brownlow, M.Jimenez, JP.Lee, DC.Pena, G.Dickey, CA.Gordon, MN.Morgan, D. Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy. Neuro-degenerative diseases. 11(4): 165-81, 2013.
  • Selenica, ML.Alvarez, JA.Nash, KR.Lee, DC.Cao, C.Lin, X.Reid, P.Mouton, PR.Morgan, D.Gordon, MN. Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain. Journal of neuroinflammation. 10(): 86, 2013.
  • Lee, DC.Rizer, J.Hunt, JB.Selenica, ML.Gordon, MN.Morgan, D. Review: experimental manipulations of microglia in mouse models of Alzheimer's pathology: activation reduces amyloid but hastens tau pathology. Neuropathology and applied neurobiology. 39(1): 69-85, 2013.
  • Lee, DC.Ruiz, CR.Lebson, L.Selenica, ML.Rizer, J.Hunt, JB.Rojiani, R.Reid, P.Kammath, S.Nash, K.Dickey, CA.Gordon, M.Morgan, D. Aging enhances classical activation but mitigates alternative activation in the central nervous system. Neurobiology of aging. 34(6): 1610-20, 2013.
  • Nash, KR.Lee, DC.Hunt, JB.Morganti, JM.Selenica, ML.Moran, P.Reid, P.Brownlow, M.Guang-Yu Yang, C.Savalia, M.Gemma, C.Bickford, PC.Gordon, MN.Morgan, D. Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy. Neurobiology of aging. 34(6): 1540-8, 2013.
  • Carty, N.Nash, KR.Brownlow, M.Cruite, D.Wilcock, D.Selenica, ML.Lee, DC.Gordon, MN.Morgan, D. Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice. PloS one. 8(3): e59626, 2013.

  • Positions Held
  • Professor (Department of Pharmacology and Therapeutics, University of South Florida 2005 - 2006)
  • Associate Professor (Department of Pharmacology and Therapeutics, University of South Florida 2000 - 2005)
  • Assistant Professor (Department of Pharmacology and Therapeutics, University of South Florida 1994 - 2000)
  • Visiting Assistant Professor (Department of Pharmacology and Therapeutics, University of South Florida 1992 - 1994)
  • Research Assistant Professor (School of Gerontology, University of Southern California 1989 - 1992)
  • Postgraduate Researcher (Brain Research Institute, University of California, Los Angeles 1985 - 1989)


  • Memberships
  • American Society for Neural Therapy and Repair (Member, 2008 - Present)
  • Society for Neuroscience (member, 1980 - Present)


  • Awards/Honors
  • Silver Performance Award for Outstanding Contributions (University of South Florida Health - 2007)
  • Travel Award (University of Michigan Claude D. Pepper Geriatrics Research and Training Center - 1992)
  • Travel Award (American Society of Neurochemistry - 1989)
  • Postdoctoral Fellowship (Brain Research Institute and Department of Anatomy, University of California at Los Angeles - 1987)
  • Postdoctoral Fellowship (Mental Retardation Research Center, University of California at Los Angeles - 1985)
  • Predoctoral Fellowship (Andrus Gerontology Center, University of Southern California - 1982)
  • Teaching Assistant Fellowship (Department of Biological Sciences, University of Southern California - 1978)


  • Lectures
  • "Monocytes, Gene Therapy and Alzheimer’s Disease" USF Dept of Molecular Medicine. FL, United States - 2013.
  • "Monocytes as Gene Therapy Vectors in Models of Alzheimers Disease" University of Texas Health Science Center at San Antonio, Department of Physiology. TX, United States - 2010.
  • "Use of monocytes to deliver gene therapy treatment in transgenic mouse models of amyloid deposition" USF-Byrd Center Symposium . FL, United States - 2008.
  • "Immunotherapy for Alzheimers Disease" Center for Aging and Brain Repair, University of South Florida. FL, United States - 2008.
  • "Genetics and Heredity" University of South Florida, Division of Comparative Biomedicine. FL, United States - 2008.
  • "Use of monocytes to deliver gene therapy treatment in transgenic mouse models of amyloid deposition" -US International Alzheimers Disease Symposium. FL, United States - 2008.

  • Profile last modified on 01/21/2014