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Marcia Gordon, Ph.D.
Professor, Department of Molecular Pharmacology and Physiology

Primary Department: COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

Professor
COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

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Contacts
Email: mgordon@health.usf.edu
Phone: (813) 974-9926
Office: ALZ, 443
Mailing address USF Health Byrd Alzheimer's Institute 4001 E. Fletcher Ave.
Tampa, FL 33613
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Education
  • PHD, Molecular Biology, University Of Southern California, Los Angeles, CA, United States - 1985.
  • B.S., Psychobiology, University of Southern California, USA - 1978.
  •  
    Interdisciplinary & Emerging Signature Programs
    Cellular and Molecular Biology, Neurodegenerative Disease, Neuroscience.
     
    Research Summary

    * Experimental therapeutics for Alzheimer's disease using animal models
    * Role of glial cells and neuroinflammation in neurodegeneration
    * Development of neuroprotective therapeutics

     


    Selected Publications
  • Joly-Amado A, Brownlow M, Pierce J, Ravipati A, Showalter E, Li Q, Gordon MN, Morgan D. Intraventricular human immunoglobulin distributes extensively but fails to modify amyloid in a mouse model of amyloid deposition. Current Alzheimer research. 11(7) : 664-71, 2014.
  • Selenica ML, Davtyan H, Housley SB, Blair LJ, Gillies A, Nordhues BA, Zhang B, Liu J, Gestwicki JE, Lee DC, Gordon MN, Morgan D, Dickey CA. Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis. Journal of neuroinflammation. 11: 152, 2014.
  • Brownlow ML, Joly-Amado A, Azam S, Elza M, Selenica ML, Pappas C, Small B, Engelman R, Gordon MN, Morgan D. Partial rescue of memory deficits induced by calorie restriction in a mouse model of tau deposition. Behavioural brain research. 271: 79-88, 2014.
  • Lee DC, Ruiz CR, Lebson L, Selenica ML, Rizer J, Hunt JB, Rojiani R, Reid P, Kammath S, Nash K, Dickey CA, Gordon M, Morgan D. Aging enhances classical activation but mitigates alternative activation in the central nervous system. Neurobiology of aging. 34(6) : 1610-20, 2013.
  • Lee DC, Rizer J, Hunt JB, Selenica ML, Gordon MN, Morgan D. Review: experimental manipulations of microglia in mouse models of Alzheimer's pathology: activation reduces amyloid but hastens tau pathology. Neuropathology and applied neurobiology. 39(1) : 69-85, 2013.
  • Brownlow ML, Benner L, D'Agostino D, Gordon MN, Morgan D. Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology. PloS one. 8(9) : e75713, 2013.
  • Carty N, Nash KR, Brownlow M, Cruite D, Wilcock D, Selenica ML, Lee DC, Gordon MN, Morgan D. Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice. PloS one. 8(3) : e59626, 2013.
  • Selenica ML, Alvarez JA, Nash KR, Lee DC, Cao C, Lin X, Reid P, Mouton PR, Morgan D, Gordon MN. Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain. Journal of neuroinflammation. 10: 86, 2013.
  • Selenica ML, Brownlow M, Jimenez JP, Lee DC, Pena G, Dickey CA, Gordon MN, Morgan D. Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy. Neuro-degenerative diseases. 11(4) : 165-81, 2013.
  • Nash KR, Lee DC, Hunt JB, Morganti JM, Selenica ML, Moran P, Reid P, Brownlow M, Guang-Yu Yang C, Savalia M, Gemma C, Bickford PC, Gordon MN, Morgan D. Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy. Neurobiology of aging. 34(6) : 1540-8, 2013.

  • Positions Held
  • Professor (Department of Pharmacology and Therapeutics, University of South Florida 2005 - 2006)
  • Associate Professor (Department of Pharmacology and Therapeutics, University of South Florida 2000 - 2005)
  • Assistant Professor (Department of Pharmacology and Therapeutics, University of South Florida 1994 - 2000)
  • Visiting Assistant Professor (Department of Pharmacology and Therapeutics, University of South Florida 1992 - 1994)
  • Research Assistant Professor (School of Gerontology, University of Southern California 1989 - 1992)
  • Postgraduate Researcher (Brain Research Institute, University of California, Los Angeles 1985 - 1989)


  • Memberships
  • Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART (Member, 2014 - Present)
  • Alliance of Women Alzheimer's Researchers (AWARE) (Member, 2014 - Present)
  • American Society for Neural Therapy and Repair (Member, 2008 - Present)
  • Society for Neuroscience (member, 1980 - Present)


  • Awards/Honors
  • Silver Performance Award for Outstanding Contributions (University of South Florida Health - 2007)
  • Travel Award (University of Michigan Claude D. Pepper Geriatrics Research and Training Center - 1992)
  • Travel Award (American Society of Neurochemistry - 1989)
  • Postdoctoral Fellowship (Brain Research Institute and Department of Anatomy, University of California at Los Angeles - 1987)
  • Postdoctoral Fellowship (Mental Retardation Research Center, University of California at Los Angeles - 1985)
  • Predoctoral Fellowship (Andrus Gerontology Center, University of Southern California - 1982)
  • Teaching Assistant Fellowship (Department of Biological Sciences, University of Southern California - 1978)


  • Lectures
  • "Monocytes, Gene Therapy and Alzheimer’s Disease" USF Dept of Molecular Medicine. FL, United States - 2013.
  • "Monocytes as Gene Therapy Vectors in Models of Alzheimers Disease" University of Texas Health Science Center at San Antonio, Department of Physiology. TX, United States - 2010.
  • "Use of monocytes to deliver gene therapy treatment in transgenic mouse models of amyloid deposition" USF-Byrd Center Symposium . FL, United States - 2008.
  • "Immunotherapy for Alzheimers Disease" Center for Aging and Brain Repair, University of South Florida. FL, United States - 2008.
  • "Genetics and Heredity" University of South Florida, Division of Comparative Biomedicine. FL, United States - 2008.
  • "Use of monocytes to deliver gene therapy treatment in transgenic mouse models of amyloid deposition" -US International Alzheimers Disease Symposium. FL, United States - 2008.

  • Profile last modified on 01/07/2015