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Juan Sanchez-Ramos, MD, PhD
Professor, Neurology

Administrative Appointment: Endowed Chair



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Email: jsramos@health.usf.edu
Phone: (813) 974-5841
Office: FOB, 4105
Mailing address 13320 Laurel Drive
Tampa, FL 33612
View My C.V.
  • MD, Medicine, University Of Illinois, Chicago, United States - 1981.
  • PhD, Pharmacology and Physiology, University of Chicago, USA - 1976.
  • PHD, University Of Chicago*, United States - 1976.
    Interdisciplinary & Emerging Signature Programs
    Research Summary

    Neurodegeneration, neurotoxicology and adult stem cell biology

    Personal Page:   http://personal.health.usf.edu/jsramos/index%20Neon%20Neurons.htm

    Selected Publications
  • Sanchez-Ramos JZ. Neon neurons. Neurology. 80(19) : 1815, 2013.
  • Song S, Song S, Cao C, Lin X, Li K, Sava V, Sanchez-Ramos J. Hippocampal neurogenesis and the brain repair response to brief stereotaxic insertion of a microneedle. Stem cells international. 2013: 205878, 2013.
  • Catlow BJ, Song S, Paredes DA, Kirstein CL, Sanchez-Ramos J. Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning. Experimental brain research. 228(4) : 481-91, 2013.
  • Velez-Lago FM, Thompson A, Oyama G, Hardwick A, Sporrer JM, Zeilman P, Foote KD, Bowers D, Ward HE, Sanchez-Ramos J, Okun MS. Differential and better response to deep brain stimulation of chorea compared to dystonia in Huntington's disease. Stereotactic and functional neurosurgery. 91(2) : 129-33, 2013.
  • Pennington A, Sava V, Song S, Patel N, Sanchez-Ramos J. Direct Actions of Granulocyte-Colony Stimulating Factor on Human Neuronal and Monocytic Cell Lines J Alzheimers Dis Parkinsonism. 3: 121, 2013.
  • Darwin K, Nichols P, Brocht A, Dorsey ER, Beck C, Biglan K, and Shoulson I,. Treatment of chorea in Huntington disease Neurotherapeutics. 10(1) : 173, 2013.
  • Huntington Study Group COHORT Investigators. Natural history of Huntington disease JAMA Neurol. 70(12) : 1520-30, 2013.
  • Shijie Song, Amanda Rowe, Kunyu Li, Vasyl Sava and J. Sanchez-Ramos. Neuroprotective effects of bone marrow stromal cells in cocultures of fetal dopaminergic neurons Journal of Neurodegeneration and Regeneration. : 27-36, 2013.
  • Briony Catlow, Shijie Song, Daniel Paredes, Cheryl Kirstein and J. Sanchez-Ramos. Effect of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning Exp. Brain Research. 228: 481-91, 2013.
  • Nichols P, Darwin K, Brocht A, Dorsey ER, Beck C, Biglan K, and Shoulson I. Safety of tetrabenazine in a longitudinal cohort study of individuals with Huntington disease Neurotherapeutics. 10(1) : 172-3, 2013.
  • Sanchez-Ramos J, Cimino C, Avila R, Rowe A, Chen R, Whelan G, Lin X, Cao C, Ashok R. Pilot study of granulocyte-colony stimulating factor for treatment of Alzheimer's disease. Journal of Alzheimer's disease : JAD. 31(4) : 843-55, 2012.
  • Weyna DR, Cheney ML, Shan N, Hanna M, Zaworotko MJ, Sava V, Song S, Sanchez-Ramos JR. Improving Solubility and Pharmacokinetics of Meloxicam via Multiple-Component Crystal Formation. Molecular pharmaceutics. : , 2012.
  • Huntington Study Group COHORT Investigators. Characterization of a large group of individuals with huntington disease and their relatives enrolled in the COHORT study. PLos One. 7(2) : e29522, 2012.
  • Sanchez-Ramos J, Reimer D, Zesiewicz T, Sullivan K, Nausieda PA. Quantitative analysis of tremors in welders. International journal of environmental research and public health. 8(5) : 1478-90, 2011.
  • Song S, Sava V, Rowe A, Li K, Cao C, Mori T, Sanchez-Ramos J. Granulocyte-colony stimulating factor (G-CSF) enhances recovery in mouse model of Parkinson's disease. Neuroscience letters. 487(2) : 153-7, 2011.
  • Apostolatos H, Apostolatos A, Vickers T, Watson JE, Song S, Vale F, Cooper DR, Sanchez-Ramos J, Patel NA. Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35. The Journal of biological chemistry. 285(34) : 25987-95, 2010.
  • Arendash GW, Sanchez-Ramos J, Mori T, Mamcarz M, Lin X, Runfeldt M, Wang L, Zhang G, Sava V, Tan J, Cao C. Electromagnetic field treatment protects against and reverses cognitive impairment in Alzheimer's disease mice. Journal of Alzheimer's disease : JAD. 19(1) : 191-210, 2010.
  • Catlow BJ, Badanich KA, Sponaugle AE, Rowe AR, Song S, Rafalovich I, Sava V, Kirstein CL, Sanchez-Ramos J. Effects of MDMA ("ecstasy") during adolescence on place conditioning and hippocampal neurogenesis. European journal of pharmacology. 628(1-3) : 96-103, 2010.
  • Butterfield LC, Cimino CR, Oelke LE, Hauser RA, Sanchez-Ramos J. The independent influence of apathy and depression on cognitive functioning in Parkinson's disease. Neuropsychology. 24(6) : 721-30, 2010.
  • Roscoe LA, Corsentino E, Watkins S, McCall M, Sanchez-Ramos J. Well-being of family caregivers of persons with late-stage Huntington's disease: lessons in stress and coping. Health communication. 24(3) : 239-48, 2009.
  • Sanchez-Ramos J, Song S, Sava V, Catlow B, Lin X, Mori T, Cao C, Arendash GW. Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice. Neuroscience. 163(1) : 55-72, 2009.
  • Catlow BJ, Rowe AR, Clearwater CR, Mamcarz M, Arendash GW, Sanchez-Ramos J. Effects of environmental enrichment and physical activity on neurogenesis in transgenic PS1/APP mice. Brain research. 1256: 173-9, 2009.
  • Sanchez-Ramos J, Song S, Cao C, Arendash G. The potential of hematopoietic growth factors for treatment of Alzheimer's disease: a mini-review. BMC neuroscience. 9 Suppl 2: S3, 2008.
  • Song S, Sanchez-Ramos J. Preparation of neural progenitors from bone marrow and umbilical cord blood. Methods in molecular biology (Clifton, N.J.). 438: 123-34, 2008.
  • Sava V, Velasquez A, Song S, Sanchez-Ramos J. Dieldrin elicits a widespread DNA repair and antioxidative response in mouse brain. Journal of biochemical and molecular toxicology. 21(3) : 125-35, 2007.
  • Sava V, Velasquez A, Song S, Sanchez-Ramos J. Adult hippocampal neural stem/progenitor cells in vitro are vulnerable to the mycotoxin ochratoxin-A. Toxicological sciences : an official journal of the Society of Toxicology. 98(1) : 187-97, 2007.
  • Song S, Song S, Zhang H, Cuevas J, Sanchez-Ramos J. Comparison of neuron-like cells derived from bone marrow stem cells to those differentiated from adult brain neural stem cells. Stem cells and development. 16(5) : 747-56, 2007.
  • Walczak P, Chen N, Eve D, Hudson J, Zigova T, Sanchez-Ramos J, Sanberg PR, Sanberg CD, Willing AE. Long-term cultured human umbilical cord neural-like cells transplanted into the striatum of NOD SCID mice. Brain research bulletin. 74(1-3) : 155-63, 2007.
  • Zesiewicz TA, Ward CL, Hauser RA, Sanchez-Ramos J, Staffetti JF, Sullivan KL. A double-blind placebo-controlled trial of zonisamide (zonegran) in the treatment of essential tremor. Movement disorders : official journal of the Movement Disorder Society. 22(2) : 279-82, 2007.
  • Vesely BA, Alli A, Song S, Sanchez-Ramos J, Fitz SR, Gower WR, Vesely DL. Primary malignant tumors of the heart: four cardiovascular hormones decrease the number and DNA synthesis of human angiosarcoma cells. Cardiology. 105(4) : 226-33, 2006.
  • Zesiewicz TA, Sullivan KL, Hauser RA, Sanchez-Ramos J. Open-label pilot study of levetiracetam (Keppra) for the treatment of chorea in Huntington's disease. Movement disorders : official journal of the Movement Disorder Society. 21(11) : 1998-2001, 2006.
  • Sanchez-Ramos J. Stem cells from umbilical cord blood. Seminars in reproductive medicine. 24(5) : 358-69, 2006.
  • Kamath SG, Chen N, Enkemann SA, Sanchez-Ramos J. Transcriptional profile of NeuroD expression in a human fetal astroglial cell line. Gene expression. 12(2) : 123-36, 2005.
  • Sava V, Mosquera D, Song S, Cardozo-Pelaez F, Sánchez-Ramos JR. Effects of melanin and manganese on DNA damage and repair in PC12-derived neurons. Free radical biology & medicine. 36(9) : 1144-54, 2004.
  • Song S, Sanchez-Ramos J. Brain as the Sea of Marrow. Experimental neurology. 184(1) : 54-60, 2003.
  • Willing AE, Vendrame M, Mallery J, Cassady CJ, Davis CD, Sanchez-Ramos J, Sanberg PR. Mobilized peripheral blood cells administered intravenously produce functional recovery in stroke. Cell transplantation. 12(4) : 449-54, 2003.
  • Mosquera DI, Stedeford T, Cardozo-Pelaez F, Sanchez-Ramos J. Strain-specific differences in the expression and activity of Ogg1 in the CNS. Gene expression. 11(1) : 47-53, 2003.
  • Sanchez-Ramos JR. Neural cells derived from adult bone marrow and umbilical cord blood. Journal of neuroscience research. 69(6) : 880-93, 2002.
  • Cardozo-Pelaez F, Stedeford TJ, Brooks PJ, Song S, Sánchez-Ramos JR. Effects of diethylmaleate on DNA damage and repair in the mouse brain. Free radical biology & medicine. 33(2) : 292-8, 2002.
  • Zigova T, Song S, Willing AE, Hudson JE, Newman MB, Saporta S, Sanchez-Ramos J, Sanberg PR. Human umbilical cord blood cells express neural antigens after transplantation into the developing rat brain. Cell transplantation. 11(3) : 265-74, 2002.

  • Positions Held
  • Associate Professor (Neurology, University of Miami 1987 - 1996)
  • Post-doctoral Fellow (Neurology, University of Miami 1985 - 1987)
  • Neurology Resident (Neurology, University of Chicago 1982 - 1985)
  • Intern (Medicine, University of Chicago 1981 - 1982)

  • Memberships
  • American Neurological Association (Fellow, 1992 - Present)
  • Movement Disorder Society (Member, 1986 - Present)
  • American Academy of Neurology (Active Member, 1985 - Present)
  • American Association for the Advancement of Science (Member, 1976 - Present)

  • Awards/Honors
  • Award for animation entitled “Dancing DNA” (University of Chicago, Sights and Sounds of Science Competition - 2004)
  • Outstanding Research Award for Nationally Recognized Research (Unviersity of South Florida - 2003)
  • Helen Ellis Endowed Chair (University of South Floria - 1996)
  • "Prix de la qualite de la Realisation technique" (Concours Interanationale des Technologie de la Creation, Paris, France - 1991)
  • Clinical Investigator Development Award (NIH - 1989)
  • Bertram A. Richardson Foreign Scholarship (University of Illinois College of Medicine - 1981)
  • James Scholar Program of Independent Studies (University of Illinois College of Medicine - 1978)
  • NIH Pre-doctoral Fellowship (University of Chicago, Dept of Pharmacological and Physiological Sciences - 1971)

  • Patents & Licensing
  • “Promotion of Brain Self-Repair by Stereotaxic Micro Stimulation” (Song S, Sanchez-Ramos J. - 2013)
  • Divalent-Metal Coated Nanoparticles For Delivery Of Compositions Into The Central Nervous System By (Sanchez-Ramos, J Sava, V, Song S, Mohapatra, S. - 2013)
  • Nervous Tissue Electrode Device (Sanchez-Ramos, J. Richard Heller and Mark Jaroszeski - 2007)
  • “Bone Marrow Cells as a Source of Neurons for Brain and Spinal Cord Repair” (Sanchez-Ramos J, Song S, Sanberg P Janssen W, Freeman T - 2003)
  • “A Method of Treating Chemical Dependency in Mammals and A Composition Thereof” (Mash D, Sanchez-Ramos J, Hearn L - 2002)

  • Lectures
  • "Effects of G-CSF on Mouse Hippocampal Neurogenesis" International Society for Stem Cell Research 7th Annual Meeting . Spain - 2009.
  • "Parkinsons Disease and Fall Risk" 10th Annual VA/USF Falls Conference. FL, United States - 2009.
  • "Filgastrim (G-CSF) increases hippocampal neurogenesis" Society for Neuroscience. DC, United States - 2008.
  • "G-CSF Reduces Brain Amyloid, Increases Expression of Synaptophysin and Improves Cognition in a Mouse Model of Alzheimers Disease" 9th International Conference on Alzheimers Disease Drug Discovery. NY, United States - 2008.

  • Profile last modified on 01/13/2014