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Yu Chen, PHD

Primary Department: COLLEGE OF MEDICINE MOLECULAR MEDICINE

Assoc Professor, COLLEGE OF MEDICINE MOLECULAR MEDICINE

Assoc Professor, COLLEGE OF MEDICINE INTERNAL MEDICINE

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Contacts
Email: ychen1@health.usf.edu
Phone: (813) 974-7809
Office: MDC, 3522
Mailing address 12901 Bruce B. Downs Blvd MDC07
Tampa, FL 33612
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Education
  • PhD, Biochemistry, University Of Chicago, Chicago, United States - 2002.
  • BS, Biochemistry and Molecular Biology, Peking University, Beijing, People's Republic of China - 1997.
 
 
Research Summary

The Chen lab (http://www.thechenlab.com) focuses on structure-based drug design against proteins involved in infectious diseases and cancer. We utilize a multi-disciplinary approach, combining biochemistry, structural biology and computational chemistry, to investigate the function and inhibition of enzymes related to bacterial cell wall synthesis, the biological process targeted by antibiotics such as penicillin. We also study human signal transduction proteins in collaboration with other laboratories. Our research goals include: Studying molecular interactions at atomic and ultimately subatomic scale through ultra-high resolution X-ray crystallography; Developing fragment-based molecular docking for drug discovery; Identifying novel inhibitors as potential drug leads and chemical probes for proteins of biomedical importance.

 
Links
Personal Page:   http://www.thechenlab.com/
Lab Link:  http://www.thechenlab.com/


Selected Publications

Positions Held
  • Post Doctoral Fellow (Pharmaceutical Chemistry, University of California, San Francisco 2003 - 2009)
  • Post Doctoral Fellow (Biochemistry and Molecular Biology, University of Chicago, 2003 - 2003)

Memberships
  • American Chemical Society (Member, 2009 - Present)




Profile last modified on 04/13/2015