University of South Florida

University of South Florida


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Thomas Taylor-Clark, PHD

Primary Department: COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

Associate Chair for Research, COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

Professor, COLLEGE OF MEDICINE MOLECULAR PHARMACOLOGY & PHYSIOLOGY

Academic Email : ttaylorclark@usf.edu

Phone : (813) 974-7749 ext. 81300

Office : MDC, 4046

Mailing address : 12901 Bruce B Downs Blvd
Tampa, FL 33612

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Education

  • PHD, Pharmacology, University College London, London, Uk - 2004.

Research summary

  • Our interests lie in the role of nociceptive (defensive) sensory nerves in health and disease. Aberrant nociceptor stimulation contributes to unpleasant/debilitating sensations and inappropriate reflexes. Our focus is primarily on the sensory nerves of the airways. Activation of these nerves leads to cough, mucus secretion, bronchospasm, wheeze. In addition, activation of airway nerves contributes to autonomic regulatory control of the heart. To gain understanding of these events we study the electrical excitability of sensory nerves, investigating the interaction of inflammation, oxidative stress and inhaled pollutants (e.g. particulate matter and ozone) on receptors and ion channels expressed on nociceptive sensory nerves. Using a combination of electrophysiological, imaging and molecular biological techniques we are able to study ion channel/receptor function and nerve activation at multiple levels, from single channels to single cells to intact tissue to preclinical models.

Selected Publications

Positions Held

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease, Cardiovascular, Environmental & Global Health, Neuroscience, Pulmonary Physiology.

Lectures

  • "Airway sensory nerve activation by endogenous activators of TRPA1 channels" Department of Integrative Biology and Pharmacology, University of Texas Health Science Center . TX, United States - 2009.
  • "Airway sensory nerve activation by endogenous activators of TRPA1 channels" Department of Pharmacology, University of Texas Health Science Center. TX, United States - 2009.
  • "Airway sensory nerve activation by endogenous activators of TRPA1 channels" Ion Channel Research Group, Duke University. NC, United States - 2009.

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Profile last modified on 01/29/2020