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Amorce Lima,  MS


Primary Department:

Graduate Research Assistant
COLLEGE OF MEDICINE MOLECULAR MEDICINE

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Contacts
Email: alima@health.usf.edu
Phone: (813) 974-8588
Office: MDC, 4007
Mailing address 144 SW Essex Dr.
Port Saint Lucie, FL 34984
 
Education
 
Interdisciplinary & Emerging Signature Programs
Allergy, Immunology & Infectious Disease.
 
Research Summary

My research focuses on the Zebrafish (Danio rerio) embryo model to study Bartonella henselae infection and host response. B. henselae infection causes a wide range of symptoms ranging from the self-limiting Cat Scratch disease to a more severe Bacillary Angiomatosis seen primarily in immunocompromised individuals. BA is characterized by tumor-like lesions at the site of infection. Several virulence factors have been characterized in B. henselae and associated with Bartonella-induced pathogenesis. To date, there has not been a practical in vivo model to reproduce the characteristics of human infection with B. henselae. As a vertebrate, the zebrafish embryo model offers various characteristics, which make it a suitable model to study Bartonella infection and host response. They share similarities with the human immune system; their ex-utero development makes it much easier for genetic manipulation and their transparency at the embryo stage makes them very suitable for microscopic analysis.

 


Profile last modified on 07/23/2013