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Stephen B. Liggett, MD

Administrative Appointment: Assoc Vice President

Vice Dean for Research, Morsani College of Medicine

Professor, Molecular Pharmacology & Physiology

Professor, Internal Medicine

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Email: sliggett@health.usf.edu
Phone: (813) 974-7715
Office: CMS, 3014
Mailing address 12901 Bruce B. Downs Blvd., MDC02
Tampa, FL 33612
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  • MD, Medicine, Unviersity Of Miami School Of Medicine, Miami, United States - 1982.
Interdisciplinary & Emerging Signature Programs
Allergy, Immunology & Infectious Disease, Cardiovascular.
Research Summary

Dr. Stephen B. Liggett's laboratory has several major interrelated initiatives: The study of the molecular basis of G-protein coupled receptor structure and function Delineation and characterization of human genetic variants within this receptor signaling network Association studies of genetic variants with heart and lung disease and their response to treatment to develop a platform for genetically-based personalized medicine Creation of genetically modified mice to define the mechanisms of heart and lung disease and "humanized mice" to explore the effects of genetic variation of human genes Determination of the full genome sequences of human Rhinoviruses using high throughput next-generation sequencing technologies; analysis of the relationships between viral genomes and asthma phenotypes Genomic-based drug discovery, most recently identifying bitter taste receptors on airway smooth muscle and showing that they act to bronchodilate, thus being a potential new therapy for asthma and COPD


Lab Link:  http://health.usf.edu/research/personalized_medicine/index.htm

Selected Publications

Positions Held

Profile last modified on 10/22/2015