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Yiru Qin,

Primary Department:

Graduate Research Assistant

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Email: yqin@health.usf.edu
Phone: (813) 974-9209
Office: MDC, 3045
Mailing address 12901 Bruce B. Downs Blvd MDC 3045
Tampa, FL 33612
  • MS, Molecular Medicine, University of South Florida, USA - 2014.
  • Bachelor, Pharmaceutical Engineering, Beijing University of Chemical Technology, Beijing, People's Republic of China - 2010.
    Interdisciplinary & Emerging Signature Programs
    Biomedical Engineering & Nanomedicine.
    Research Summary

    My project focuses on developing a graphene materials-based theranostic strategy for ovarian cancer. Initially, I synthesized the graphene-based material from graphite by a one-step hydrothermal method and evaluate the immunotoxicity of this nanomaterial in macrophages. Secondly, the nanomaterial was conjugated with targeting ligands and therapeutic drugs. The imaging and specific therapeutic effect of the conjugates were measured in ovarian cancer cells. Last, the therapeutic efficacy and pharmacokinetic profiles of this conjugates will be evaluated in nude mice models


    Lab Link:  http://hsccf.hsc.usf.edu/researchdirectory/directorysearch/search_profile.cfm?person_id=2837593

    Selected Publications
  • Qin Y, Zhou ZW, Pan ST, He ZX, Zhang X, Qiu JX, Duan W, Yang T, Zhou SF. Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in activated THP-1 macrophages. Toxicology. 327: 62-76, 2015.
  • Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells. Drug design, development and therapy. 9: 1601-26, 2015.
  • Na I, Redmon D, Kopa M, Qin Y, Xue B, Uversky VN. Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology. PloS one. 8(8) : e73476, 2013.

  • Memberships
  • AAPS (Member, 2014 - Present)

  • Profile last modified on 04/10/2015