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Jia-Wang Wang, PhD

Primary Department: COLLEGE OF MEDICINE INTERNAL MEDICINE

Assistant Professor, COLLEGE OF MEDICINE INTERNAL MEDICINE

Assistant Professor, COLLEGE OF MEDICINE PEDIATRICS

Assistant Professor, Division of Allergy and Immunology, Internal Medicine, Morsani College of Medicine

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Contacts
Email: jwang@health.usf.edu
Phone: (813) 974-7521
Office: MDC, 4128
Mailing address Division of Allergy and Immunology 12901 Bruce B Downs Blvd
Tampa, FL 33612
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Education
  • Post doc, Immunology, University of Pennsylvania, USA - 2000.
  • Post doc, Molecular Oncology, Chinese Academy of Medical Sciences, Beijing, People's Republic of China - 1996.
  • PHD, Virology & Molecular Biology, Wuhan University, Wuhan, China - 1994.
  • MSc, Genetics, Sichuan University, ChengDu, People's Republic of China - 1989.
 
Interdisciplinary & Emerging Signature Programs
Allergy, Immunology & Infectious Disease.
 
Research Summary

MicroRNAs (miRs) are ~22 nucleotides long non-coding RNAs that inhibit mRNA translation by the base pairing rule at the accuracy of one base. As each miR may regulate hundreds of genes, and each gene may be regulated by multiple miRs, it is believed that most human genes and the entire spectrum of biological pathways are tightly and delicately controlled by the miRNome. Deregulation of miRs may contribute to various diseases. We work on inflammation regulators responsive to lipopolysaccharide stimulation (Science 2002 295:2094-7, J Immunol 2001 166:4586-95, Oncogene 2004 23:4089-97). We found that SH2-containing inositol phosphatase (SHIP) plays an important role in two processes that limit the success of allogeneic marrow transplantation: graft rejection and graft-versus-host disease using Cre/loxP conditional knockout mouse models, and discovered a novel gene: LPS-responsive beige-like anchor (Lrba) that may be involved in leading intracellular vesicles to activated receptor complexe

 
Links

Lab Link:  http://www.usfinternalmedicine.com


Selected Publications

Positions Held

Memberships
  • Austin Journal of Clinical Immunology (Editorial board member, 2013 - Present)
  • Moffitt Cancer Biology and Evolution Program (Collaborator Member, 2012 - Present)
  • The American Academy of Allergy Asthma and Immunology (Member, 2006 - Present)



Patents & Licensing
  • Micro-RNAS Modulating Immunity and Inflammation United States Patent Application (Shyam S Mohapatra, Jia-Wang Wang - 2013)
  • 1. LPS-Responsive CHS1/Beige-Like Anchor Gene and Therapeutic Applications (William G. Kerr, Jia-Wang Wang - 2010)


Profile last modified on 10/28/2015