University of South Florida

University of South Florida

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Jay Dean, Ph.D.


Professor (with tenure), Dept. of Molecular Pharmacology & Physiology, College of Medicine

Adjunct Professor, Department of Military and Emergency Medicine


Academic Email :

Phone : (813) 974-1547

Office : MDL, 1020

Mailing address : 12901 Bruce B. Downs Blvd. MDC 7
Tampa, FL 33612

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  • PHD, Physiology, The Ohio State University, Columbus, United States - 1986.
  • MS, Respiration Physiology, Michigan Technological University, USA - 1981.
  • B.S., Biology, Central Michigan University, USA - 1979.

Academic Philosophy

  • To train and educate future physiologists and biomedical professionals in the theory, principles and practices of physiology while fostering an academic environment that encourages scientific discovery and appreciation for our scientific heritage.

Research summary

  • We study the effects of O2, CO2 and barometric pressure on the function of the mammalian CNS, with an emphasis on the cardio-respiratory and gastro-esophageal control systems. Ongoing research focuses on understanding how hyperoxia and hypercapnia interact to generate reactive O2 and N2 species that, in turn, activate neuronal activity in the brain stem. This research has relevance to understanding normal and abnormal function in cardio-respiratory control during periods of disordered breathing, environmental stresses, and in understanding neurological problems arising from the use of hyperoxia in clinical medicine and combat operations. We are particularly interested in the following: 1) neurophysiology of CNS oxygen toxicity (seizures); 2) understanding how CO2 and H-ions are “sensed” by chemoreceptor neurons in the caudal brain stem; and 3) understanding how gastro-esophageal CO2 ventilation supplements pulmonary ventilation during chronic respiratory acidosis.

Selected Publications

Positions Held

  • Vice-Chair of Administration and Professor (Department of Anatomy and Physiology, School of Medicine, Wright State University 2005 - 2006)
  • Director (Environmental & Hyperbaric Cell Biology Facility, Wright State University 2000 - 2006)
  • Acting-Chair and Professor (Dept. of Anatomy and Physiology, School of Medicine, Wright State University 2003 - 2004)
  • Professor (Department of Physiology and Biophysics, School of Medicine, Wright State University 2002 - 2003)
  • Associate Professor (with tenure) (Department of Physiology and Biophysics, School of Med., Wright State University 1997 - 2002)
  • Assist. Professor (Department of Physiology and Biophysics, Wright State University 1991 - 1997)
  • Research Assist. Prof. (Dept. of Physiology, Univ. of North Carolina 1991 - 1991)

Interdisciplinary and Emerging Signature Programs

  • Cancer Biology, Cardiovascular, Cellular and Molecular Biology, Environmental & Global Health, Neuroscience, Neuroscience, Other, Oxygen Toxicity, Pulmonary Physiology, Allergy, Immunology & Infectious Disease.


  • Journal of Applied Physiology (Associate Editor, 2008 - Present)
  • American Journal of Biomedical Sciences (Member of Editorial Board, 2008 - Present)
  • Undersea and Hyperbaric Medicine (Member of Editorial Board, 2002 - Present)
  • Journal of Applied Physiology (Member of Editorial Board, 1999 - 2008)


  • Faculty Excellence Award Winner (SW Ohio Council for Higher Education - 2004)
  • Brage Golding Distinguished Professor of Research (Wright State University - 2003)
  • Award for Outstanding Excellence in Research and Medical Education (Wright State University, School of Medicine - 1999)
  • Clifford W. Perry Award (UNC-CH) (North Carolina Affiliate American Lung Association Grant-in-Aid of Research - 1990)
  • Presidential Predoctoral Fellow (Ohio State University - 1984)


Profile last modified on 03/08/2016