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Shyam Mohapatra, PHD
Distinguished Professor, Univ of South Florida
Associate Dean, Graduate Programs, College of Pharmacy
Vice Chair of Research, Internal Med, Medicine
Director,USF Nanomedicine Research Center , Internal Medicine, Medicine
Distinguished Health Professor, Internal Medicine
Director, Div Translational Medicine, Internal Medicine
Research Career Scientist, Research and Development
Principal Investigator, VA Research & Development

Administrative Appointment: Endowed Chair
Primary Department: COLLEGE OF MEDICINE INTERNAL MEDICINE

Distinguished Professor
COLLEGE OF MEDICINE INTERNAL MEDICINE

Distinguished Professor
COP DEPT OF PHARMACEUTICAL SCIENCE

Distinguished Professor
NON USF HEALTH

Professor
COLLEGE OF MEDICINE MOLECULAR MEDICINE

Professor
COLLEGE OF MEDICINE PEDIATRICS

Professor
COPH ENVIRONMENTAL & OCCUPATIONAL HEALTH

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Contacts
Email: smohapat@health.usf.edu
Phone: (813) 974-8568
Office: MDC, 3149
Mailing address 12908 Bruce B. Downs Blvd MDC 19
Tampa, FL 33612
View My C.V.
 
Education
  • MBA, Leadership & Management, University of South Florida, USA - 1999.
  • PHD, Botany, Australian National University, Australia - 1984.
  • MS, Genetics/Statistics, GB Plant University of Agril & Technology, Pantnagar, India - 1978.
  • BS, Biology, Orissa univeristy of Agril & Technology, Bhubaneswar, India - 1976.
  •  
    Interdisciplinary & Emerging Signature Programs
    Asthma Center of Excellence, Allergy, Immunology & Infectious Disease, Biomedical Engineering & Nanomedicine, Cancer Biology, Neurodegenerative Disease, Other, Women & Children's Health.
     
    Academic Philosophy

    My passion for academia is based on my personal belief that each student has the potential to bring something unique and special to the world.I believe in “no student left behind”. Through education each student must self-discover his/her potential.

     
    Research Summary

    My research focuses on immunology and inflammation in allergic, immunologic and infectious viral diseases and cancers. The current research programs include: molecular biology and genetics of IgE responsiveness, molecular mechanisms of virus infection, development of prophylactic/therapeutic gene transfer, development of genetic antivirals, molecular basis of genetic predisposition to inflammatory diseases and application of nanotechnology to biomedicine.

     
    Links
    Personal Page:   http://health.usf.edu/medicine/spaiid/index.htm
    Lab Link:  http://http://health.usf.edu/medicine/internalmedicine/tmd/faculty.html


    Selected Publications
  • Dixon AE, Castro M, Cohen RI, Gerald LB, Holbrook JT, Irvin CG, Mohapatra S, Peters SP, Rayapudi S, Sugar EA, Wise RA. Reply. The Journal of allergy and clinical immunology. 136(1) : 212-3, 2015.
  • Dixon AE, Castro M, Cohen RI, Gerald LB, Holbrook JT, Irvin CG, Mohapatra S, Peters SP, Rayapudi S, Sugar EA, Wise RA. Efficacy of nasal mometasone for the treatment of chronic sinonasal disease in patients with inadequately controlled asthma. The Journal of allergy and clinical immunology. 135(3) : 701-9.e5, 2015.
  • Anne E. Dixon, Mario Castro, Rubin I. Cohen, Lynn B. Gerald, Janet T. Holbrook, Charles G. Irvin, Shyam Mohapatra, Stephen P. Peters, Sobharani Rayapudi, Elizabeth A. Sugar, Robert A. Wise. Efficacy of nasal mometasone for the treatment of chronic sinonasal disease in patients with inadequately controlled asthma Journal of Allergy and Clinical Immunology. : http://dx.doi.org/10.1016/j.jaci.2014.06.038, 2014.
  • Lloyd MC, Burke N, Kalantarpour F, Niesen MI, Hall A, Pennypacker K, Citron B, Pick CG, Adams V, Das M, Mohapatra S, Cualing H, Blanck G. QUANTITATIVE MORPHOLOGICAL AND MOLECULAR PATHOLOGY OF THE HUMAN THYMUS CORRELATE WITH INFANT CAUSE OF DEATH Technol Innov. 16(1) : 55–62, 2014.
  • Bird GH, Boyapalle S, Wong T, Opoku-Nsiah K, Bedi R, Crannell WC, Perry AF, Nguyen H, Sampayo V, Devareddy A, Mohapatra S, Mohapatra SS, Walensky LD. Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection. The Journal of clinical investigation. 124(5) : 2113-24, 2014.
  • Das M, Wang C, Bedi R, Mohapatra SS, Mohapatra S. Magnetic micelles for DNA delivery to rat brains after mild traumatic brain injury. Nanomedicine : nanotechnology, biology, and medicine. 10(7) : 1539–1548, 2014.
  • Wong TM, Boyapalle S, Sampayo V, Nguyen HD, Bedi R, Kamath SG, Moore ML, Mohapatra S, Mohapatra SS. Respiratory syncytial virus (RSV) infection in elderly mice results in altered antiviral gene expression and enhanced pathology. PloS one. 9(2) : e88764, 2014.
  • Terianne M. Wong, Sandhya Boyapalle, Siddarth Kamath, Huy Nguyen, Subhra Mohapatra, Shyam S. Mohapatra. Differential Gene Expression in Young Vs Aged Mice Infected with Respiratory Syncytial Virus (meeting abstract) Journal of Allergy and Clinical Immunology. 131(2) : AB8, 2013.
  • Srinivas Nagaraj, Allison Nelson, Subhra Mohapatra, and Shyam Mohapatra. Role of NPRA in MDSC mediated suppression in cancer (P2071) (meeting abstract) Journal of Immunology. 190: 53.36, 2013.
  • Yin JJ, Sharma S, Shumyak SP, Wang ZX, Zhou ZW, Zhang Y, Guo P, Li CZ, Kanwar JR, Yang T, Mohapatra SS, Liu W, Duan W, Wang JC, Li Q, Zhang X, Tan J, Jia L, Liang J, Wei MQ, Li X, Zhou SF. Synthesis and biological evaluation of novel folic acid receptor-targeted, β-cyclodextrin-based drug complexes for cancer treatment. PloS one. 8(5) : e62289, 2013.
  • Chunyan Wang, Sowndharya Ravi, Ujjwala Sree Garapati, Mahasweta Das, Mark Howell, Jaya Mallela, Subbiah Alwarappan, Shyam S. Mohapatra. Multifunctional chitosan magnetic-graphene (CMG) nanoparticles: a theranostic platform for tumor-targeted co-delivery of drugs, genes and MRI contrast agents J. Mater. Chem. B. 1: 4396-4405, 2013.
  • Michael B. Cheung, Subhra Mohapatra, Shyam S. Mohapatra. Respiratory Syncytial Virus (RSV) Infection and Replication in Mesenchymal Stem Cells (MSCs)(meeting abstract) Journal of Allergy and Clinical Immunology. 131(2) : AB74, 2013.
  • Mallela J, Ravi S, Jean Louis F, Mulaney B, Cheung M, Sree Garapati U, Chinnasamy V, Wang C, Nagaraj S, Mohapatra SS, Mohapatra S. Natriuretic peptide receptor A signaling regulates stem cell recruitment and angiogenesis: a model to study linkage between inflammation and tumorigenesis. Stem cells (Dayton, Ohio). 31(7) : 1321-9, 2013.
  • Alwarappan, Subbiah; Das, Mahaswetha; Mohapatra, Shyam; Li, Chen-Zhong. Peripheral Neural Devices: State-of-the-Art Journal of Neuroscience and Neuroengineering. 2(6) : 517-531, 2013.
  • Girard YK, Wang C, Ravi S, Howell MC, Mallela J, Alibrahim M, Green R, Hellermann G, Mohapatra SS, Mohapatra S. A 3D fibrous scaffold inducing tumoroids: a platform for anticancer drug development. PloS one. 8(10) : e75345, 2013.
  • Subhra Mohapatra, Srinivas Nagaraj, Shyam S. Mohapatra. Nano/bio interface: impact on drug delivery applications Drug Delivery and Translational Research. 3(4) : 295-296, 2013.
  • Huls NF, Phan MH, Kumar A, Mohapatra S, Mohapatra S, Mukherjee P, Srikanth H. Transverse susceptibility as a biosensor for detection of Au-Fe₃O₄ nanoparticle-embedded human embryonic kidney cells. Sensors (Basel, Switzerland). 13(7) : 8490-500, 2013.
  • Mhaskar R, Alandikar V, Emmanuel P, Djulbegovic B, Patel S, Patel A, Naik E, Mohapatra S, Kumar A. Adherence to antiretroviral therapy in India: a systematic review and meta-analysis. Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine. 38(2) : 74-82, 2013.
  • Suraj Dixit, Mahasweta Das, Subbiah Alwarappan, Nancy L. Goicochea, Mark Howell, Subhra Mohapatra, Shyam Mohapatra. Phospholipid micelle encapsulated gadolinium oxide nanoparticles for imaging and gene delivery RSC Adv. 3(8) : 2727-2735, 2013.
  • Aljubran SA, Cox R, Tamarapu Parthasarathy P, Kollongod Ramanathan G, Rajanbabu V, Bao H, Mohapatra SS, Mohapatra SM, Lockey R, Kolliputi N. Enhancer of zeste homolog 2 induces pulmonary artery smooth muscle cell proliferation. PloS one. 7(5) : e37712, 2012.
  • Boyapalle S, Mohapatra S, Mohapatra S. Nanotechnology Applications to HIV Vaccines and Microbicides. Journal of global infectious diseases. 4(1) : 62-8, 2012.
  • Boyapalle S, Wong T, Garay J, Teng M, San Juan-Vergara H, Mohapatra S, Mohapatra S. Respiratory syncytial virus NS1 protein colocalizes with mitochondrial antiviral signaling protein MAVS following infection. PloS one. 7(2) : e29386, 2012.
  • Brar T, Nagaraj S, Mohapatra S. Microbes and asthma: the missing cellular and molecular links. Current opinion in pulmonary medicine. 18(1) : 14-22, 2012.
  • San-Juan-Vergara H, Sampayo-Escobar V, Reyes N, Cha B, Pacheco-Lugo L, Wong T, Peeples ME, Collins PL, Castaño ME, Mohapatra SS. Cholesterol-rich microdomains as docking platforms for respiratory syncytial virus in normal human bronchial epithelial cells. Journal of virology. 86(3) : 1832-43, 2012.
  • Alwarappan S, Cissell K, Dixit S, Mohapatra S, Li CZ. Chitosan-Modified Graphene Electrodes for DNA Mutation Analysis. Journal of electroanalytical chemistry (Lausanne, Switzerland). 686: 69-72, 2012.
  • Das M, Mohapatra S, Mohapatra SS. New perspectives on central and peripheral immune responses to acute traumatic brain injury. Journal of neuroinflammation. 9: 236, 2012.
  • Leonardo CC, Musso J, Das M, Rowe DD, Collier LA, Mohapatra S, Pennypacker KR. CCL20 Is Associated with Neurodegeneration Following Experimental Traumatic Brain Injury and Promotes Cellular Toxicity In Vitro. Translational stroke research. 3(3) : 357-63, 2012.
  • Subbiah Alwarappan, Sandhya Boyapalle, Ashok Kumar, Chen-Zhong Li, and Shyam Mohapatra. Comparative Study of Single-, Few-, and Multilayered Graphene toward Enzyme Conjugation and Electrochemical Response Journal of Physical Chemistry C. 116(11) : 6556-6559 , 2012.
  • Subbiah Alwarappan, Shree R Singh, Shreekumar Pillai, Ashok Kumar, Shyam Mohapatra. Direct Electrochemistry of Glucose Oxidase at a Gold Electrode Modified with Graphene Nanosheets Analytical Letters. 45(7) : 746-753, 2012.
  • Mahasweta Das, Subhra Mohapatra and Shyam S Mohapatra. New perspectives on central and peripheral immune responses to acute traumatic brain injury Journal of Neuroinflammation. 9: 236, 2012.
  • Tina Brar, Srinivas Nagaraj, and Shyam Mohapatra. Microbes and Asthma in the Elderly: The Missing Cellular and Molecular Links Curr Opin Pulm Med. 18(1) : 14-22, 2012.
  • Allison Nelson, Jim Parkerson, Richard F. Lockey, Subhra Mohapatra, Shyam Mohapatra, and Srinivas Nagaraj. Role of Myeloid Derived Suppressor Cells in Asthma (meeting abstract) World Allergy Organ J. 5: S26, 2012.
  • Jia-Wang Wang, Kunyu Li, Gary Hellermann, Richard F. Lockey, Subhra Mohapatra, and Shyam Mohapatra. MIR-150 Suppresses Lung Inflammation in a Mouse Model of Experimental Asthma World Allergy Organ J. 5: S26, 2012.
  • Jia-Wang Wang, Kunyu Li, Richard F. Lockey, Subhra Mohapatra, and Shyam Mohapatra. A Highly Sensitive and Specific Universal Mirna Profiling Method World Allergy Organ J. 5: S55, 2012.
  • Michel Alkhalil, Mathew Varghese, Gary Hellermann, Shyam Mohapatra, Ahmed Butt, and Richard F. Lockey. Measurement of Long-acting Natriuretic Peptide (Lanp) in Exacerbation of Asthma (meeting abstract) World Allergy Organ J. 5: S195–S196, 2012.
  • Kumar A, Glaum M, El-Badri N, Mohapatra S, Haller E, Park S, Patrick L, Nattkemper L, Vo D, Cameron DF. Initial observations of cell-mediated drug delivery to the deep lung. Cell transplantation. 20(5) : 609-18, 2011.
  • Das M, Leonardo CC, Rangooni S, Pennypacker KR, Mohapatra S, Mohapatra SS. Lateral fluid percussion injury of the brain induces CCL20 inflammatory chemokine expression in rats. Journal of neuroinflammation. 8: 148, 2011.
  • Wang X, Raulji P, Mohapatra SS, Patel R, Hellermann G, Kong X, Vera PL, Meyer-Siegler KL, Coppola D, Mohapatra S. Natriuretic peptide receptor a as a novel target for prostate cancer. Molecular cancer. 10: 56, 2011.
  • Zhang W, Cao X, Chen D, Wang JW, Yang H, Wang W, Mohapatra S, Hellermann G, Kong X, Lockey RF, Mohapatra SS. Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells. Genetic vaccines and therapy. 9(1) : 3, 2011.
  • Groër MW, Yolken RH, Xiao JC, Beckstead JW, Fuchs D, Mohapatra SS, Seyfang A, Postolache TT. Prenatal depression and anxiety in Toxoplasma gondii-positive women. American journal of obstetrics and gynecology. 204(5) : 433.e1-7, 2011.
  • Mohapatra SS, Qazi M, Hellermann G. Immunotherapy for allergies and asthma: present and future. Current opinion in pharmacology. 10(3) : 276-88, 2010.
  • Mohapatra S, Hellermann G. Infectious Diseases and Asthma. Preface. Immunology and allergy clinics of North America. 30(4) : xiii-xviii, 2010.
  • Wong T, Hellermann G, Mohapatra S. The infectious march: the complex interaction between microbes and the immune system in asthma. Immunology and allergy clinics of North America. 30(4) : 453-80, v, 2010.
  • Kumar A, Jena PK, Behera S, Lockey RF, Mohapatra S, Mohapatra S. Multifunctional magnetic nanoparticles for targeted delivery. Nanomedicine : nanotechnology, biology, and medicine. 6(1) : 64-9, 2010.
  • Wang X, Xu W, Kong X, Chen D, Hellermann G, Ahlert TA, Giaimo JD, Cormier SA, Li X, Lockey RF, Mohapatra S, Mohapatra SS. Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma. Respiratory research. 10: 66, 2009.
  • Mohapatra S, Juan HS. Designer monoclonal antibodies as drugs: the state of the art. Expert review of clinical immunology. 4(3) : 305-7, 2008.
  • Mohapatra SS, Boyapalle S. Epidemiologic, experimental, and clinical links between respiratory syncytial virus infection and asthma. Clinical microbiology reviews. 21(3) : 495-504, 2008.
  • Kong X, Hellermann GR, Zhang W, Jena P, Kumar M, Behera A, Behera S, Lockey R, Mohapatra SS. Chitosan Interferon-gamma Nanogene Therapy for Lung Disease: Modulation of T-Cell and Dendritic Cell Immune Responses. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology. 4(3) : 95-105, 2008.
  • Lee D, Mohapatra SS. Chitosan nanoparticle-mediated gene transfer. Methods in molecular biology (Clifton, N.J.). 433: 127-40, 2008.
  • Shirley SA, Montpetit AJ, Lockey RF, Mohapatra SS. Curcumin prevents human dendritic cell response to immune stimulants. Biochemical and biophysical research communications. 374(3) : 431-6, 2008.
  • Mohapatra SS, Lockey RF, Polo F. Weed pollen allergens. Clinical allergy and immunology. 21: 127-39, 2008.
  • Mohapatra SS, San-Juan-Vergara H, Wopfner N, Ferreira F. Experimental forms of allergen immunotherapy with modified allergens and adjuvants. Clinical allergy and immunology. 21: 393-413, 2008.
  • Mohapatra SS and Boyapalle S. Respiratory Syncytial Virus Infection and Asthma: A critical appraisal of epidemiologic, experimental and clinical link Clin Microbiol Rev. (in press) : , 2008.
  • Lima J., Mohapatra SS. Polymorphisms in the NPPA gene associate with Asthma Clinical Experimental Allergy. (in press) : , 2008.
  • Mohapatra SS and Lockey RF. Respiratory Syncytial Virus Infection from biology to prophylaxis: A perspective World Allergy Organization Journal. (in press) : , 2008.
  • Kumar A., Fal-Miyar V., Garcia JA., Cerdeira A., Mohapatra SS. Magnetoimpidance biosensor for uptake control in drug delivery Appl Phys Lett. (In Press) : , 2008.
  • Kong X., Hellermann GR, Zhang W., Jena PK, Kumar M, Behera A, Behera S, Lockey RF, Mohapatra SS. Chitosan IFN-gamma Nanogene (CIN) Therapy for Lung Disease: Modulation of T Cell and Dendritic Cell Immune Responses Allergy Asthma and Immunology. (In Press) : , 2008.
  • Kong X, Wang X, Xu W, Behera S, Hellermann G, Kumar A, Lockey RF, Mohapatra S, Mohapatra SS. Natriuretic peptide receptor a as a novel anticancer target. Cancer research. (1) : , 2008.
  • Wang X, Xu W, Mohapatra S, Kong X, Li X, Lockey RF, Mohapatra SS. Prevention of airway inflammation with topical cream containing imiquimod and small interfering RNA for natriuretic peptide receptor. Genetic vaccines and therapy. (1) : , 2008.
  • Kumar A, Aravamudhan S, Gordic M, Bhansali S, Mohapatra SS. Ultrasensitive detection of cortisol with enzyme fragment complementation technology using functionalized nanowire. Biosensors & bioelectronics. (9-10) : , 2007.
  • Aravamudhan S, Kumar A, Mohapatra S, Bhansali S. Sensitive estimation of total cholesterol in blood using Au nanowires based micro-fluidic platform. Biosensors & bioelectronics. 22(9-10) : 2289-94, 2007.
  • Kumar A, Sahoo B, Montpetit A, Behera S, Lockey RF, Mohapatra SS. Development of hyaluronic acid-Fe2O3 hybrid magnetic nanoparticles for targeted delivery of peptides. Nanomedicine : nanotechnology, biology, and medicine. (2) : , 2007.
  • Kong X, Zhang W, Lockey RF, Auais A, Piedimonte G, Mohapatra SS. Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene. Genetic vaccines and therapy. : , 2007.
  • Lee D, Zhang W, Shirley SA, Kong X, Hellermann GR, Lockey RF, Mohapatra SS. Thiolated chitosan/DNA nanocomplexes exhibit enhanced and sustained gene delivery. Pharmaceutical research. (1) : , 2007.
  • Mohapatra SS. Role of natriuretic peptide signaling in modulating asthma and inflammation. Canadian journal of physiology and pharmacology. 85(7) : 754-9, 2007.
  • Lee D, Lockey R, Mohapatra S. Folate receptor-mediated cancer cell specific gene delivery using folic acid-conjugated oligochitosans. Journal of nanoscience and nanotechnology. 6(9-10) : 2860-6, 2006.
  • Lee DW, Shirley SA, Lockey RF, Mohapatra SS. Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline. Respiratory research. : , 2006.
  • Singam R, Jena PK, Behera S, Hellermann GR, Lockey RF, Ledford D, Mohapatra SS. Combined fluticasone propionate and salmeterol reduces RSV infection more effectively than either of them alone in allergen-sensitized mice. Virology journal. 3: 32, 2006.
  • Zhang W., Lockey RF., Mohapatra SS. Respiratory Syncytial virus: Immunopathology and control Expert Review of Clinical Immunology. (2) : , 2006.
  • Kumar A., Jena PK., Behera S., Lockey RF., Mohapatra SS. Efficient DNA and Peptide Delivery by Functionalized Chitosan-coated Single Walled carbon Nanotubes Journal of Biomedical Nanotechnology. (1) : , 2006.
  • Lee D., Lockey RF., Mohapatra SS. Folate Receptor-mediated cancer cell specific gene delivery using folic acid-conjugated oligochitosans Journal of Nanoscience and Nanotechnology. (6) : , 2006.
  • Zhang W, Lockey RF, Mohapatra SS. Respiratory syncytial virus: immunopathology and control. Expert review of clinical immunology. 2(1) : 169-79, 2006.
  • Zhang W, Yang H, Kong X, Mohapatra S, San Juan-Vergara H, Hellermann G, Behera S, Singam R, Lockey RF, Mohapatra SS. Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene. Nature medicine. (1) : , 2005.
  • Kong X, Hellermann GR, Patton G, Kumar M, Behera A, Randall TS, Zhang J, Lockey RF, Mohapatra SS. An immunocompromised BALB/c mouse model for respiratory syncytial virus infection. Virology journal. 2: 3, 2005.
  • Kong, X. Hellermann, G., Patton, G., Kumar, M., Behera A, Randall TS, Zhang J. Lockey R.F., and Mohapatra SS. An Immunocompromised BALB/c Mouse Model for Respiratory Syncytial Virus Infection Virology Journal. 2: 3, 2005.
  • Mohapatra SS, Lockey RF, Shirley S. Immunobiology of grass pollen allergens. Current allergy and asthma reports. 5(5) : 381-7, 2005.
  • Ravi Kumar M, Hellermann G, Lockey RF, Mohapatra SS. Nanoparticle-mediated gene delivery: state of the art. Expert opinion on biological therapy. (8) : , 2004.
  • Hellermann G, Kong X, Gunnarsdóttir J, San Juan H, Singam R, Behera S, Zhang W, Lockey RF, Mohapatra SS. Mechanism of bronchoprotective effects of a novel natriuretic hormone peptide. The Journal of allergy and clinical immunology. 113(1) : 79-85, 2004.
  • Mohapatra SS, Lockey RF, Vesely DL, Gower WR. Natriuretic peptides and genesis of asthma: an emerging paradigm? The Journal of allergy and clinical immunology. 114(3) : 520-6, 2004.
  • Mohapatra SS, Lockey RF, Polo F. Weed pollen allergens. Clinical allergy and immunology. 18: 207-22, 2004.
  • King MJ, Bukantz SC, Phillips S, Mohapatra SS, Tamulis T, Lockey RF. Serum total IgE and specific IgE to Dermatophagoides pteronyssinus, but not eosinophil cationic protein, are more likely to be elevated in elderly asthmatic patients. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 25(5) : 321-5, 2004.
  • Zhang W, Singam R, Hellermann G, Kong X, Juan HS, Lockey RF, Wu SJ, Porter K, Mohapatra SS. Attenuation of dengue virus infection by adeno-associated virus-mediated siRNA delivery. Genetic vaccines and therapy. 2(1) : 8, 2004.
  • Kong X, San Juan H, Behera A, Peeples ME, Wu J, Lockey RF, Mohapatra SS. ERK-1/2 activity is required for efficient RSV infection. FEBS letters. (1-3) : , 2004.
  • Larché M, Ferreira F, Mohapatra SS. Modifying allergens and using adjuvants for specific immunotherapy. Clinical allergy and immunology. 18: 641-61, 2004.
  • San-Juan-Vergara H, Peeples ME, Lockey RF, Mohapatra SS. Protein kinase C-alpha activity is required for respiratory syncytial virus fusion to human bronchial epithelial cells. Journal of virology. (24) : , 2004.
  • Kuderer NM, San-Juan-Vergara HG, Kong X, Esch R, Lockey RF, Mohapatra SS. Mite and cockroach proteases activate p44/p42 MAP kinases in human lung epithelial cells. Clinical and molecular allergy : CMA. 1(1) : 1, 2003.
  • Kumar M, Kong X, Behera AK, Hellermann GR, Lockey RF, Mohapatra SS. Chitosan IFN-gamma-pDNA Nanoparticle (CIN) Therapy for Allergic Asthma. Genetic vaccines and therapy. 1(1) : 3, 2003.
  • Kong X, San Juan H, Kumar M, Behera AK, Mohapatra A, Hellermann GR, Mane S, Lockey RF, Mohapatra SS. Respiratory syncytial virus infection activates STAT signaling in human epithelial cells. Biochemical and biophysical research communications. 306(2) : 616-22, 2003.
  • Matsuse H, Kong X, Hu J, Wolf SF, Lockey RF, Mohapatra SS. Intranasal IL-12 produces discreet pulmonary and systemic effects on allergic inflammation and airway reactivity. International immunopharmacology. 3(4) : 457-68, 2003.
  • Hellermann GR, Mohapatra SS. Genetic therapy: on the brink of a new future. Genetic vaccines and therapy. 1(1) : 1, 2003.
  • Mohapatra SS. Mucosal gene expression vaccine: a novel vaccine strategy for respiratory syncytial virus. The Pediatric infectious disease journal. 22(2 Suppl) : S100-3; discussion S103-4, 2003.
  • Mohapatra SS. American Academy of Allergy, Asthma and Immunology--60th annual meeting. Advances in allergy and asthma therapy: 2003 AAAI updates. 7-12 March 2003, Denver, CO, USA. IDrugs : the investigational drugs journal. 6(5) : 423-5, 2003.
  • Kumar M, Behera AK, Lockey RF, Vesely DL, Mohapatra SS. Atrial natriuretic peptide gene transfer by means of intranasal administration attenuates airway reactivity in a mouse model of allergic sensitization. The Journal of allergy and clinical immunology. 110(6) : 879-82, 2002.
  • Mohapatra SS. Gene transfer and transcription factors. 1-6 March 2002, New York City, NY, USA. IDrugs : the investigational drugs journal. 5(4) : 312-5, 2002.
  • Behera AK, Kumar M, Lockey RF, Mohapatra SS. Adenovirus-mediated interferon gamma gene therapy for allergic asthma: involvement of interleukin 12 and STAT4 signaling. Human gene therapy. 13(14) : 1697-709, 2002.
  • Kumar M, Behera AK, Lockey RF, Zhang J, Bhullar G, De La Cruz CP, Chen LC, Leong KW, Huang SK, Mohapatra SS. Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection. Human gene therapy. 13(12) : 1415-25, 2002.
  • Hellermann GR, Nagy SB, Kong X, Lockey RF, Mohapatra SS. Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells. Respiratory research. 3: 22, 2002.
  • Behera AK, Kumar M, Lockey RF, Mohapatra SS. 2'-5' Oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells. The Journal of biological chemistry. 277(28) : 25601-8, 2002.
  • Matsuse H, Behera AK, Kumar M, Lockey RF, Mohapatra SS. Differential cytokine mRNA expression in Dermatophagoides farinae allergen-sensitized and respiratory syncytial virus-infected mice. Microbes and infection / Institut Pasteur. (7) : , 2000.
  • Mohapatra SS. Is cross-reactivity a real or an imaginary concept? The Journal of allergy and clinical immunology. 99(5) : 724, 1997.
  • Mohapatra SS. IL-12 possibilities. Science (New York, N.Y.). 269(5230) : 1499, 1995.

  • Positions Held
  • Director of Basic Research (Internal Medicine, Joy McCann Culverhouse Airway Disease Center, University of South Florida 1997 - 2008)
  • Tenured Professor (Internal Medicine, University of South Florida 2007 - 2007)
  • Mabel & Ellsworth Simmons Professor (Medicine, University of South Florida 2000 - 2007)
  • Associate Professor (Medical Microbiology & Immunology, University of South Florida 1996 - 1999)
  • Associate Professor (Internal Medicine, University of South Florida 1996 - 1999)
  • Associate Professor (with tenure) (Immunology, University of Manitoba 1992 - 1995)
  • Assistant Professor (Immunology, University of Manitoba 1988 - 1991)
  • Research Associate (Biology Department, McGill University 1986 - 1987)
  • Alexander von Humboldt rEsearch Fellow (Genetics Institute, University of Bielefeld 1984 - 1986)


  • Memberships
  • Canadian Society of Allergy and Immunology (Member, 1990 - 1995)
  • Canadian Society of Immunology (Member, 1988 - 1995)
  • European Academy of Allergology and Clinical Immunology (Member, 1995 - 1995)
  • ATS (Member, 1999 - Present)
  • Mexican Society of Allergy and Immunology (Honorary Member, 1998 - Present)
  • AAAAAI (Fellow, 1998 - Present)
  • American Association of Immunogists (Member, 1992 - Present)
  • American Academy of Allergy and Clinical Immunology (Member, 1992 - Present)
  • Pharmacia Allergy Research Foundation (Member, 1992 - Present)


  • Awards/Honors
  • Global Corporate Awards in Nanotechnology (Global Corporate Awards - 2014)
  • Inductee Florida Inventors Hall of Fame (Florida Inventors Hall of Fame - 2014)
  • Chartered Fellow (National Academy of Inventors - 2013)
  • VA Career Scientist Award (James A Haley Veterans Hospital - 2007)
  • Outstanding Biotech Achievement Award (University of South Florida - 2005)
  • Outstanding Faculty Research Achievement Award (University of South Floirda - 2005)
  • Outstanding Biotechnology Recognition Award (University of South Florida - 2004)
  • Oustanding Faculty Research Award Sigma Xi (University of South Florida - 2004)
  • Shyam Mohapatra (American Who's Who - 2000)
  • Research Grant Award (American Heart Association - 1999)
  • Veteran Administration Merit Review Award (James A Haley Veterans Hospital - 1999)
  • Career Development Award (American Lung Association - 1998)
  • Presidential Honored Research Faculty Recognition (University of South Florida - 1997)
  • Allergy Research Foundation Award (Pharmacia - 1992)
  • Merit Award (University of Manitoba - 1992)
  • Alexander von Humboldt Research Award (AvH Foundation - 1984)


  • Patents & Licensing
  • JAK/STAT inhibitors and MAPK/ERK inhibitors for RSV infection (8,592,368 - 2014)
  • Materials and methods for treatment of respiratory allergic diseases (US 8,623,835 - 2014)
  • Method of drug delivery by carbon nanotube-chitosan nanocomplexes ( US 8,536,324 - 2014)
  • Genetic adjuvants for immunotherapy (US 8,603,458 - 2014)
  • Materials and methods for prevention and treatment of RNA viral diseases (US 8,293,717 - 2013)
  • Micro-RNAs modulating immunity and inflammation (US 8,415,096 - 2013)
  • Nano-based device for detection of disease biomarkers and other target molecules ( US 8,349,604 - 2013)
  • Materials and methods for reducing inflammation by inhibition of the atrial natriuretic peptide rece (US8,071,560 - 2012)
  • Materials and methods for treatment of inflammatory and cell proliferation disorders (US 8,148,114 - 2012)
  • Materials and methods to reduce low density lipoprotein cholesterol ( US7,892,553 - 2011)
  • Integrated nanowires/microelectrode array for biosensing (US8,058,155 - 2011)
  • Material and Methods for Treatment of Allergic Diseases (USA 7655772 - 2010)
  • Genetic Adjuvants for Immunotherapy (USA 7595303 - 2009)
  • A Method of Transdermal Drug Delivery using Hyaluronic Acid Nanoparticles (USA 7371738 - 2008)
  • Materials and Methods for Prevention and Treatment of RNA Viral Disease (USA 7354908 - 2008)
  • Gene Expression Vaccine (USA 7118888 - 2006)
  • Interrupting the Interaction of Intercellular Adhesion Molecule1 and Respiratory Syncytial Virus... (USA 6900299 - 2005)
  • Method of Intranasal Gene Transfer for Protection Against Respiratory Infection. (USA 6489306 - 2002)


  • Lectures
  • "Plenary speaker on microRNA " Am Acad of Allergy, Asthma and Immunology. CA, United States - 2011.
  • "Nano-Cell Theranostics for lung diseases" American Thoracic Society. CO, United States - 2011.
  • "Preventing HIV Transmission: Progress and Perspectives" Mumbai, India. India - 2010.
  • "Healthcare Deficiencies in the South-Asthma" Southern Medical Association Asthma Assembly. FL, United States - 2010.
  • "Pharmacogenetics of Asthma and ANP pathway" Fourth Annual SIPAIID symposium on Genomics, Immunity and Infections. FL, United States - 2010.
  • "Anti-viral therapy. What is new" World Allergy Organization . Argentina - 2009.
  • "Short interference RNA (SiRNA): Potential therapy for allergy and asthma" World Allergy Organization Symposium. Argentina - 2009.
  • "Nanomedicine: Applications in diagnosis and therapy" World Allergy Organization Symposium. Argentina - 2009.
  • "Designer Antibodies" World Allergy Organization. PA, United States - 2008.
  • "siRNA in Allergic Diseases" American Academy of Allergy, Asthma and Immunology. PA, United States - 2008.
  • "Mesenchymal Stem Cells and Asthma" American Academy of Asthma, Allergy and Immunology. PA, United States - 2008.
  • "NPRA signaling in human dendritic cells controls treg development" World Allergy Organization. Thailand - 2007.
  • "A critical role for atrial natriuretic peptide receptor signaling in allergic disease" World Allergy Congress. Thailand - 2007.
  • "Nanotechnology and Asthma" AAAAI. FL, United States - 2007.
  • "The Beginning of Asthma:Role of Natriuretic Pathway" AAAAI. CA, United States - 2007.
  • "Molecular Approaches to Antiviral Therapy" AAAAI. CA, United States - 2007.
  • "Nanotechnology and Asthma" AAAAI. CA, United States - 2007.
  • "Nanotechnology Applications to Allergy and Asthma" University of Manitoba. Canada - 2006.
  • "RSV Infection and Asthma" XIV Latin American Congress. Argentina - 2006.
  • "Nanoparticles and Gene Therpay" Congress on Particles. FL, United States - 2006.
  • "Regulation of Allergic Inflmmation by Hormonal Peptides" AAAAI. FL, United States - 2006.
  • "Regulation of Allergic Inflammation by Hormonal Peptides" AAAAI. FL, United States - 2006.
  • "Nanotechnology Applciations to Allergy and Asthma" AAAAI. FL, United States - 2006.
  • "Nanotechnology in Advanced Drug Delivery" NIPER-NANO-2006 Congress. India - 2006.

  • Profile last modified on 07/13/2015