My Profile
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Kersti Linask
, PHD
Administrative Appointment: Division Chief
Primary Department: COLLEGE OF MEDICINE PEDIATRICS
Professor
COLLEGE OF MEDICINE MOLECULAR MEDICINE
Professor
COLLEGE OF MEDICINE PEDIATRICS
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| Contacts |
| Email: |
klinask@health.usf.edu
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| Phone: |
(727) 553-3636 |
| Office: |
ACH, CRI007 |
| Mailing address |
140-7th Ave South ,Children's Research Institute 2007
St. Petersburg, FL 33701
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View My C.V. |
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Education |
| PHD, University Of Pennsylvania , United States - 1986. |
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Interdisciplinary & Emerging Signature Programs |
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Biomedical Engineering & Nanomedicine, Cardiovascular. |
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Research Summary |
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My research interests focus on cellular and molecular mechanisms underlying early cardiac cell specification, differentiation, and heart organogenesis. Specifically, we target the cardiac precursor cell population. Currently, we are analyzing Fetal Alcohol Syndrome and lithium and the mechanism by which folate and with even greater efficacy, folate/myo-inositol combination prevents cardiac birth defects. These studies have been extended into wound healing. |
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Links |
Lab Link:
http://health.usf.edu/medicine/pediatrics/cardiovascular/index.htm |
Selected Publications
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Linask, KK.Manisastry, S.Han, M.
Cross talk between cell-cell and cell-matrix adhesion signaling pathways during heart organogenesis: implications for cardiac birth defects.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 11(3): 200-8, 2005.
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Linask, KK.Han, M.Cai, DH.Brauer, PR.Maisastry, SM.
Cardiac morphogenesis: matrix metalloproteinase coordination of cellular mechanisms underlying heart tube formation and directionality of looping.
Developmental dynamics : an official publication of the American Association of Anatomists. 233(3): 739-53, 2005.
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Manisastry, SM.Han, M.Linask, KK.
Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development.
Developmental dynamics : an official publication of the American Association of Anatomists. 235(8): 2160-74, 2006.
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Linask, KK.Vanauker, M.
A role for the cytoskeleton in heart looping.
TheScientificWorldJournal. 7(): 280-98, 2007.
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Garita, B.Jenkins, MW.Han, M.Zhou, C.Vanauker, M.Rollins, AM.Watanabe, M.Fujimoto, JG.Linask, KK.
Blood flow dynamics of one cardiac cycle and relationship to mechanotransduction and trabeculation during heart looping.
American journal of physiology. Heart and circulatory physiology. 300(3): H879-91, 2011.
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Grants
- INVESTIGATING THE EARLY EMBROYONIC MURINE HEART USING OPTICAL COHERENCE TOMOGRAPHY
($36,750.00,
08/05/2009-05/31/2013)
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- INVESTIGATING THE EARLY EMBROYONIC MURINE HEART USING OPTICAL COHERENCE TOMOGRAPHY
($73,500.00,
08/05/2009-05/31/2013)
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- MYO-INOSITOL PREVENTION OF CARDIAC BIRTH DEFECTS
($10,450.00,
06/01/2011-05/31/2012)
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- INVESTIGATING THE EARLY EMBROYONIC MURINE HEART USING OPTICAL COHERENCE TOMOGRAPHY
($61,750.00,
08/05/2009-05/31/2012)
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- VALIDATION OF FOLATE RESPONSIVE GENES IN CARDIAC DEVELOPMENT
($15,000.00,
07/01/2010-06/30/2011)
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- INVESTIGATING THE EARLY EMBROYONIC MURINE HEART USING OPTICAL COHERENCE TOMOGRAPHY
($36,750.00,
08/05/2009-05/31/2010)
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- METHYLATION STATUS OF HOMOCYSTEINE EXPOSED EMBRYONIC HEARTS
($14,946.00,
07/01/2007-06/30/2008)
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- FETAL CARDIAC DISEASE: EFFECTS OF ELEVATED HOMOCYSTEINE ON EARLY HEART DEVELOPMENT
($60,000.00,
07/01/2005-06/30/2008)
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- FETAL CARDIAC DISEASE: EFFECTS OF ELEVATED HOMOCYSTEINE ON EARLY HEART DEVELOPMENT
($60,000.00,
07/01/2005-06/30/2007)
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- MOLECULAR ANALYSIS OF CARDIAC FLECTIN
($14,940.00,
07/01/2004-06/30/2005)
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- CARDIAC TERATOGENICITY OF LITHIUM
($90,000.00,
07/01/2003-04/30/2005)
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- CARDIAC TERATOGENICITY OF LITHIUM
($278,075.00,
07/01/2003-04/30/2005)
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- CARDIAC TERATOGENICITY OF LITHIUM
($278,075.00,
07/01/2003-04/30/2005)
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- CARDIAC TERATOGENICITY OF LITHIUM
($206,709.00,
07/01/2003-04/30/2005)
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- BIOMECHANICS OF HEART LOOPING
($26,354.00,
07/01/2003-01/31/2005)
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Profile last modified on 02/21/2011
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