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Kendra Vehik, MPH, PhD

Primary Department: COLLEGE OF MEDICINE PEDIATRICS

Assistant Professor
COPH EPIDEMIOLOGY & BIOSTATISTICS

Associate Professor
COLLEGE OF MEDICINE PEDIATRICS

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Contacts
Email: kvehik@health.usf.edu
Office: MDC, 113
Mailing address 3650 Spectrum Blvd. STE 100
Tampa, FL 33612
 
Education
  • PhD, Analytic Health Sciences, University Of Colorado, United States - 2007.
  • Ph.D., Epidemiology, University of Colorado, USA - 2007.
  • M.P.H., Epidemiology and Biostatistics, George Washington University, USA - 1996.
  • B.S., Biology, University of Arizona, USA - 1993.
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    Research Summary

    Dr. Kendra Vehik is an Assistant Professor at the University of South Florida. Her research interests are focused on type 1 diabetes including prevention, clinical/translational and quality of life research. Much of her published work has been focused on identifying probable risk factors associated with type 1 diabetes in order to develop more directed hypotheses to prevent the onset of autoimmunity and clinical disease. She has expertise in epidemiologic and biostatistical methodologies associated with case/control, longitudinal and clinical trial designs. Dr. Vehik has firsthand knowledge and experience working with many type 1 clinical projects coordinated by the Pediatric Epidemiology Center, including The Environmental Determinants of Diabetes in the Young (TEDDY), TrialNet Network and the Diabetes Prevention Trial – Type 1 (DPT-1) studies. Her main diabetes expertise lies in identifying stable and informative risk factors and validating the identified risk factors as triggers and/or accelerators of autoimmunity and clinical disease. She has authored many high impact peer-reviewed publications that have focused on determining risk factors associated with type 1 diabetes focused on in utero and early life environmental exposures (body size and growth patterns, nutrition, infections), genetic susceptibility, clinical outcomes in delaying onset and population-based temporal trends in risk factors and type 1 diabetes. Her long time interests are in identifying early life risk factors, exploring how changes in these risk factors over time and potential gene-environment interactions contribute to the risk of autoantibody seroconversion and surrogate biomarkers for prediction, diagnosis and risk of type 1 diabetes, and delaying or stopping the onset of diabetes.

     


    Selected Publications
  • Lee HS, Burkhardt BR, McLeod W, Smith S, Eberhard C, Lynch K, Hadley D, Rewers M, Simell O, She JX, Hagopian B, Lernmark A, Akolkar B, Ziegler AG, Krischer JP. Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Diabetes/metabolism research and reviews. 30(5) : 424-34, 2014.
  • Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark A, Hagopian W, She JX, Krischer JP, Akolkar B, Schatz DA, Atkinson MA, Triplett EW. Early Childhood Gut Microbiomes Show Strong Geographic Differences Among Subjects at High Risk for Type 1 Diabetes. Diabetes care. : , 2014.
  • Elding Larsson H, Vehik K, Gesualdo P, Akolkar B, Hagopian W, Krischer J, Lernmark Å, Rewers M, Simell O, She JX, Ziegler A, Haller MJ. Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease. Pediatric diabetes. 15(2) : 118-26, 2014.
  • Hummel S, Vehik K, Uusitalo U, McLeod W, Aronsson CA, Frank N, Gesualdo P, Yang J, Norris JM, Virtanen SM. Infant feeding patterns in families with a diabetes history - observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study. Public health nutrition. 17(12) : 2853-62, 2014.
  • Lin Y, Qian X, Krischer J, Vehik K, Lee HS, Huang S. A rule-based prognostic model for type 1 diabetes by identifying and synthesizing baseline profile patterns. PloS one. 9(6) : e91095, 2014.
  • Yang J, Lernmark A, Uusitalo UM, Lynch KF, Veijola R, Winkler C, Larsson HE, Rewers M, She JX, Ziegler AG, Simell OG, Hagopian WA, Akolkar B, Krischer JP, Vehik K. Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes. International journal of obesity (2005). 38(12) : 1491-6, 2014.
  • Liu E, Lee HS, Aronsson CA, Hagopian WA, Koletzko S, Rewers MJ, Eisenbarth GS, Bingley PJ, Bonifacio E, Simell V, Agardh D. Risk of pediatric celiac disease according to HLA haplotype and country. The New England journal of medicine. 371(1) : 42-9, 2014.
  • Aronsson CA, Vehik K, Yang J, Uusitalo U, Hay K, Joslowski G, Riikonen A, Ballard L, Virtanen SM, Norris JM. Use of dietary supplements in pregnant women in relation to sociodemographic factors - a report from The Environmental Determinants of Diabetes in the Young (TEDDY) study. Public health nutrition. 16(8) : 1390-402, 2013.
  • Andrén Aronsson C, Uusitalo U, Vehik K, Yang J, Silvis K, Hummel S, Virtanen SM, Norris JM. Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes. Maternal & child nutrition. : , 2013.
  • Adl AA, Qian X, Xu P, Vehik K, Krischer JP. Feature ranking based on synergy networks to identify prognostic markers in DPT-1. EURASIP journal on bioinformatics & systems biology. 2013(1) : 12, 2013.
  • Vehik K, Fiske SW, Logan CA, Agardh D, Cilio CM, Hagopian W, Simell O, Roivainen M, She JX, Briese T, Oikarinen S, Hyoty H, Ziegler AG, Rewers M, Lernmark A, Akolkar B, Krischer JP, Burkhardt BR. Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY. Diabetes/metabolism research and reviews. 29(7) : 557-67, 2013.
  • Vehik K, Ajami NJ, Hadley D, Petrosino JF, Burkhardt BR. The changing landscape of type 1 diabetes: recent developments and future frontiers. Current diabetes reports. 13(5) : 642-50, 2013.
  • Vehik K, Dabelea D. Why are C-section deliveries linked to childhood type 1 diabetes? Diabetes. 61(1) : 36-7, 2012.
  • Baxter J, Vehik K, Johnson SB, Lernmark B, Roth R, Simell T. Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: the TEDDY Study. Contemporary clinical trials. 33(4) : 633-40, 2012.
  • Vehik K, Cuthbertson D, Boulware D, Beam CA, Rodriguez H, Legault L, Hyytinen M, Rewers MJ, Schatz DA, Krischer JP. Performance of HbA1c as an early diagnostic indicator of type 1 diabetes in children and youth. Diabetes care. 35(9) : 1821-5, 2012.
  • Salami F, Abels M, Hyöty H, Vaziri-Sani F, Aronsson C, Vehik K, Delli A, Hagopian W, Rewers M, Ziegler A, Simell O, Akolkar B, Krischer J, She J, Lernmark A. DETECTION OF LACTOBACILLI IN MONTHLY MAIL-IN STOOL SAMPLES FROM 3-18 MONTHS OLD INFANTS AT GENETIC RISK FOR TYPE 1 DIABETES. International journal of probiotics & prebiotics. 7(3-4) : 135-144, 2012.
  • Jaiswal M, Crume T, Vehik K, Scherzinger A, Stamm E, Hamman RF, Dabelea D. Is low birth weight associated with adiposity in contemporary U.S. youth? The Exploring Perinatal Outcomes among Children (EPOCH) Study. Journal of developmental origins of health and disease. 3(3) : 166-72, 2012.
  • Vehik K, Dabelea D. The changing epidemiology of type 1 diabetes: why is it going through the roof? Diabetes/metabolism research and reviews. 27(1) : 3-13, 2011.
  • Vehik K, Haller MJ, Beam CA, Schatz DA, Wherrett DK, Sosenko JM, Krischer JP. Islet autoantibody seroconversion in the DPT-1 study: justification for repeat screening throughout childhood. Diabetes care. 34(2) : 358-62, 2011.
  • Vehik K, Cuthbertson D, Ruhlig H, Schatz DA, Peakman M, Krischer JP. Long-term outcome of individuals treated with oral insulin: diabetes prevention trial-type 1 (DPT-1) oral insulin trial. Diabetes care. 34(7) : 1585-90, 2011.
  • Vehik K, Beam CA, Mahon JL, Schatz DA, Haller MJ, Sosenko JM, Skyler JS, Krischer JP. Development of autoantibodies in the TrialNet Natural History Study. Diabetes care. 34(9) : 1897-901, 2011.
  • Richesson R, Vehik K. Patient registries: utility, validity and inference. Advances in experimental medicine and biology. 686: 87-104, 2010.
  • Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith GJ, Dabelea D. Childhood growth and age at diagnosis with Type 1 diabetes in Colorado young people. Diabetic medicine : a journal of the British Diabetic Association. 26(10) : 961-7, 2009.
  • Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith GJ, Rewers M, Dabelea D. Trends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetes. Diabetes care. 31(7) : 1392-6, 2008.
  • Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith G, Bloch C, Rewers M, Dabelea D. Increasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youth. Diabetes care. 30(3) : 503-9, 2007.

  • Lectures
  • "Islet antibody remission and risk of type 1 diabetes in very young patients in the TEDDY Study" Immunology of Diabetes Society . Australia - 2013.
  • "Early infant feeding and islet autoimmunity in The Environmental Determinants of Diabetes in the You" Immunology of Diabetes Society (co-presenter). Australia - 2013.
  • "The six-year incidence of diabetes associated autoantibodies in the genetically at-risk: The TEDDY S" Immunology of Diabetes Society (co-presenter). Australia - 2013.
  • "Increased weight or height gain in infants or toddlers does not predict early development of T1D: Th" Immunology of Diabetes Society (co-presenter). Australia - 2013.
  • "Prevalence of obesity in young children genetically at-risk for type 1 diabetes (co-presenter)" American Diabetes Association. PA, United States - 2012.
  • "Rising hemoglobin A1c in the non-diabetic range accelerates time to development of type 1 diabetes i" European Diabetes Epidemiology Group Meeting (co-presenter). United Kingdom - 2012.
  • "Requirements and strategy for the development of a pediatric drug ontology (co-presenter)" Int’l Conference on Formal Ontology in Information Systems. Austria - 2012.

  • Profile last modified on 01/06/2015