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Michael Teng,  PhD
Associate Professor, Internal Medicine, Morsani College of Medicine


Assoc Professor

Assoc Professor

Assoc Professor

Assoc Professor

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Email: mteng@health.usf.edu
Phone: (813) 974-5184
Office: MDC, 3146
Mailing address 12901 Bruce B. Downs Blvd. MDC 19
Tampa, FL 33612
View My C. V.
  • PhD, Immunology, University Of Chicago , Chicago, United States - 1993.
  • Ph.D., Immunology, University of Chicago ,USA - 1993.
  • B.S., Life Sciences, MIT ,USA - 1988.
    Interdisciplinary & Emerging Signature Programs
    Biomedical Engineering & Nanomedicine, Allergy, Immunology & Infectious Disease.
    Research Summary

    We study the role of host-virus interactions in viral pathogenesis. In particular, we are interested in how respiratory syncytial virus affects host signal transduction pathways to enhance viral replication. We use a combination of biochemical, molecular and cell biological, and virological techniques to examine these questions.


    Lab Link:  http://www.usfinternalmedicine.com

    Selected Publications
  • Webster Marketon, JI.Corry, J.Teng, MN. The respiratory syncytial virus (RSV) nonstructural proteins mediate RSV suppression of glucocorticoid receptor transactivation. Virology. 449(): 62-9, 2014.
  • Jillian N. Whelan , Kim C. Tran , Ruan R. Cox Jr , Damian B. van Rossum , Randen L. Patterson , Michael Teng Exploitation Of The Host Ubiquitin System By Respiratory Syncytial Virus Nonstructural Protein 2 Journal of Allergy and Clinical Immunology. 133(2): AB283, 2014.
  • Phan, SI.Chen, Z.Xu, P.Li, Z.Gao, X.Foster, SL.Teng, MN.Tripp, RA.Sakamoto, K.He, B. A respiratory syncytial virus (RSV) vaccine based on parainfluenza virus 5 (PIV5). Vaccine. 32(25): 3050-7, 2014.
  • Fuentes, S.Crim, RL.Beeler, J.Teng, MN.Golding, H.Khurana, S. Development of a simple, rapid, sensitive, high-throughput luciferase reporter based microneutralization test for measurement of virus neutralizing antibodies following Respiratory Syncytial Virus vaccination and infection. Vaccine. 31(37): 3987-94, 2013.
  • Michael Teng, David J. Fitzhugh, Kim Tran, Richard F. Lockey, Peter Collins Functional Characterization of A Cis-Acting Temperature Sensitive Mutation From A Respiratory Syncytial Virus Vaccine Candidate Journal of Allergy and Clinical Immunology. 131(2): AB11, 2013.
  • Tian, B.Zhao, Y.Kalita, M.Edeh, CB.Paessler, S.Casola, A.Teng, MN.Garofalo, RP.Brasier, AR. CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells. Journal of virology. 87(12): 7075-92, 2013.
  • Anne L. Hotard, Fyza Y. Shaikh, Sujin Lee, Dan Yan, Michael N. Teng, Richard K. Plemper, James E. Crowe Jr., Martin L. Moore A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis Virology. 434(1): 129–136, 2012.
  • Wu, W.Tran, KC.Teng, MN.Heesom, KJ.Matthews, DA.Barr, JN.Hiscox, JA. The Interactome of the Human Respiratory Syncytial Virus NS1 Protein Highlights Multiple Effects on Host Cell Biology. Journal of virology. 86(15): 7777-89, 2012.
  • Teng, MN. The non-structural proteins of RSV: targeting interferon antagonists for vaccine development. Infectious disorders drug targets. 12(2): 129-37, 2012.
  • Kim Tran, Sandra Fuentes, Biao He and Michael Teng Inhibition of AKT Kinase Activity Decreases Replication of Human Respiratory Syncytial Virus World Allergy Organ J. (5): S63–S64, 2012.
  • Abhijeet Bakre, Patricia Mitchell, Jonathan K. Coleman, Les P. Jones, Geraldine Saavedra, Michael Teng, S. Mark Tompkins, Respiratory syncytial virus modifies microRNAs regulating host genes that affect virus replication J Gen Virol. 93(): 2346-2356, 2012.
  • Reena Ghildyal, Kim C. Tran, Michael N. Teng, Leon Caly, Hongmei Li, John Mills and David A. Jans Nucleocytoplasmic trafficking of the matrix protein of respiratory syncytial virus: Role in infection J Antivir Antiretrovir. 4(4): , 2012.
  • Sandhya Boyapalle, Terianne Wong, Julio Garay, Michael Teng, Homero San Juan-Vergara, Subhra Mohapatra, Shyam Mohapatra Respiratory Syncytial Virus NS1 Protein Colocalizes with Mitochondrial Antiviral Signaling Protein MAVS following Infection PLoS ONE. 7(2): e29386, 2012.
  • Hanley, LL.McGivern, DR.Teng, MN.Djang, R.Collins, PL.Fearns, R. Roles of the respiratory syncytial virus trailer region: effects of mutations on genome production and stress granule formation. Virology. 406(2): 241-52, 2010.
  • Ghildyal, R.Ho, A.Dias, M.Soegiyono, L.Bardin, PG.Tran, KC.Teng, MN.Jans, DA. The respiratory syncytial virus matrix protein possesses a Crm1-mediated nuclear export mechanism. Journal of virology. 83(11): 5353-62, 2009.
  • Ling, Z.Tran, KC.Teng, MN. Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I. Journal of virology. 83(8): 3734-42, 2009.
  • Ling, Z.Tran, KC.Arnold, JJ.Teng, MN. Purification and characterization of recombinant human respiratory syncytial virus nonstructural protein NS1. Protein expression and purification. 57(2): 261-70, 2008.
  • Sun, M.Fuentes, SM.Timani, K.Sun, D.Murphy, C.Lin, Y.August, A.Teng, MN.He, B. Akt plays a critical role in replication of nonsegmented negative-stranded RNA viruses. Journal of virology. 82(1): 105-14, 2008.
  • Tran, KC.He, B.Teng, MN. Replacement of the respiratory syncytial virus nonstructural proteins NS1 and NS2 by the V protein of parainfluenza virus 5. Virology. 368(1): 73-82, 2007.
  • Fuentes, S.Tran, KC.Luthra, P.Teng, MN.He, B. Function of the respiratory syncytial virus small hydrophobic protein. Journal of virology. 81(15): 8361-6, 2007.
  • Ghildyal, R.Li, D.Peroulis, I.Shields, B.Bardin, PG.Teng, MN.Collins, PL.Meanger, J.Mills, J. Interaction between the respiratory syncytial virus G glycoprotein cytoplasmic domain and the matrix protein. The Journal of general virology. 86(Pt 7): 1879-84, 2005.
  • Tran, KC.Collins, PL.Teng, MN. Effects of altering the transcription termination signals of respiratory syncytial virus on viral gene expression and growth in vitro and in vivo. Journal of virology. 78(2): 692-9, 2004.
  • Johnson, TR.Teng, MN.Collins, PL.Graham, BS. Respiratory syncytial virus (RSV) G glycoprotein is not necessary for vaccine-enhanced disease induced by immunization with formalin-inactivated RSV. Journal of virology. 78(11): 6024-32, 2004.
  • Spann, KM.Collins, PL.Teng, MN. Genetic recombination during coinfection of two mutants of human respiratory syncytial virus. Journal of virology. 77(20): 11201-11, 2003.
  • Teng, MN.Collins, PL. The central conserved cystine noose of the attachment G protein of human respiratory syncytial virus is not required for efficient viral infection in vitro or in vivo. Journal of virology. 76(12): 6164-71, 2002.
  • Polack, FP.Teng, MN.Collins, PL.Prince, GA.Exner, M.Regele, H.Lirman, DD.Rabold, R.Hoffman, SJ.Karp, CL.Kleeberger, SR.Wills-Karp, M.Karron, RA. A role for immune complexes in enhanced respiratory syncytial virus disease. The Journal of experimental medicine. 196(6): 859-65, 2002.

  • Positions Held
  • Assistant Professor (Internal Medicine, College of Medicine, USF 2010 - 2012)
  • Assistant Professor (Biochemistry and Molecular Biology, Eberly College of Science, Pennsylvania State University 2002 - 2010)

  • Memberships
  • American Society for Virology (Member, 2004 - Present)
  • American Society for Microbiology (Member, 2000 - Present)
  • American Association for the Advancement of Science (Member, 1994 - Present)

  • Profile last modified on 04/02/2015