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John Cannon, PHD

Primary Department: COLLEGE OF MEDICINE PEDIATRICS

Assistant Professor
COLLEGE OF MEDICINE PEDIATRICS

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Contacts
Email: jcannon@health.usf.edu
Mailing address 140 7th Ave S CRI-3008
St. Petersburg, FL 33701
 
Education
  • PHD, Baylor College Of Medicine, United States - 1997.
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    Research Summary

    Regulation of the immune response by germline-encoded innate immune receptors

     


    Selected Publications
  • Haire RN, Cannon JP, O'Driscoll ML, Ostrov DA, Mueller MG, Turner PM, Litman RT, Litman GW, Yoder JA. Genomic and functional characterization of the diverse immunoglobulin domain-containing protein (DICP) family. Genomics. 99(5) : 282-91, 2012.
  • Cannon JP, O'Driscoll M, Litman GW. Specific lipid recognition is a general feature of CD300 and TREM molecules. Immunogenetics. 64(1) : 39-47, 2012.
  • Cannon JP, O'Driscoll M, Litman GW. Construction, expression, and purification of chimeric protein reagents based on immunoglobulin fc regions. Methods in molecular biology (Clifton, N.J.). 748: 51-67, 2011.
  • Schreeder DM, Cannon JP, Wu J, Li R, Shakhmatov MA, Davis RS. Cutting edge: FcR-like 6 is an MHC class II receptor. Journal of immunology (Baltimore, Md. : 1950). 185(1) : 23-7, 2010.
  • Cannon JP, Dishaw LJ, Haire RN, Litman RT, Ostrov DA, Litman GW. Recognition of additional roles for immunoglobulin domains in immune function. Seminars in immunology. 22(1) : 17-24, 2010.
  • Dishaw LJ, Ota T, Mueller MG, Cannon JP, Haire RN, Gwatney NR, Litman RT, Litman GW. The basis for haplotype complexity in VCBPs, an immune-type receptor in amphioxus. Immunogenetics. 62(9) : 623-31, 2010.
  • Litman GW, Cannon JP. Immunology: Immunity's ancient arms. Nature. 459(7248) : 784-6, 2009.
  • Cannon JP. Plasticity of the immunoglobulin domain in the evolution of immunity. Integrative and comparative biology. 49(2) : 187-96, 2009.
  • Cannon JP, Haire RN, Magis AT, Eason DD, Winfrey KN, Hernandez Prada JA, Bailey KM, Jakoncic J, Litman GW, Ostrov DA. A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition. Immunity. 29(2) : 228-37, 2008.
  • Yoder JA, Cannon JP, Litman RT, Murphy C, Freeman JL, Litman GW. Evidence for a transposition event in a second NITR gene cluster in zebrafish. Immunogenetics. 60(5) : 257-65, 2008.
  • Dishaw LJ, Mueller MG, Gwatney N, Cannon JP, Haire RN, Litman RT, Amemiya CT, Ota T, Rowen L, Glusman G, Litman GW. Genomic complexity of the variable region-containing chitin-binding proteins in amphioxus. BMC genetics. 9: 78, 2008.
  • Litman GW, Dishaw LJ, Cannon JP, Haire RN, Rast JP. Alternative mechanisms of immune receptor diversity. Current opinion in immunology. 19(5) : 526-34, 2007.
  • Litman GW, Cannon JP, Dishaw LJ, Haire RN, Eason DD, Yoder JA, Prada JH, Ostrov DA. Immunoglobulin variable regions in molecules exhibiting characteristics of innate and adaptive immune receptors. Immunologic research. 38(1-3) : 294-304, 2007.
  • Ostrov DA, Hernández Prada JA, Haire RN, Cannon JP, Magis AT, Bailey K, Litman GW. Crystallization and X-ray diffraction analysis of a novel immune-type receptor from Ictalurus punctatus and phasing by selenium anomalous dispersion methods. Acta crystallographica. Section F, Structural biology and crystallization communications. 63(Pt 12) : 1035-7, 2007.
  • Hernández Prada JA, Haire RN, Allaire M, Jakoncic J, Stojanoff V, Cannon JP, Litman GW, Ostrov DA. Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus. Nature immunology. 7(8) : 875-82, 2006.
  • Cannon JP, Haire RN, Mueller MG, Litman RT, Eason DD, Tinnemore D, Amemiya CT, Ota T, Litman GW. Ancient divergence of a complex family of immune-type receptor genes. Immunogenetics. 58(5-6) : 362-73, 2006.
  • Cannon JP, Haire RN, Pancer Z, Mueller MG, Skapura D, Cooper MD, Litman GW. Variable domains and a VpreB-like molecule are present in a jawless vertebrate. Immunogenetics. 56(12) : 924-9, 2005.
  • Litman GW, Cannon JP, Dishaw LJ. Reconstructing immune phylogeny: new perspectives. Nature reviews. Immunology. 5(11) : 866-79, 2005.
  • Litman GW, Cannon JP, Rast JP. New insights into alternative mechanisms of immune receptor diversification. Advances in immunology. 87: 209-36, 2005.
  • Cannon JP, Haire RN, Schnitker N, Mueller MG, Litman GW. Individual protochordates have unique immune-type receptor repertoires. Current biology : CB. 14(12) : R465-6, 2004.
  • Cannon JP, Haire RN, Rast JP, Litman GW. The phylogenetic origins of the antigen-binding receptors and somatic diversification mechanisms. Immunological reviews. 200: 12-22, 2004.
  • Hernández Prada JA, Haire RN, Cannon JP, Litman GW, Ostrov DA. Crystallization and preliminary X-ray analysis of VCBP3 from Branchiostoma floridae. Acta crystallographica. Section D, Biological crystallography. 60(Pt 11) : 2022-4, 2004.
  • Eason DD, Cannon JP, Haire RN, Rast JP, Ostrov DA, Litman GW. Mechanisms of antigen receptor evolution. Seminars in immunology. 16(4) : 215-26, 2004.
  • Litman GW, Yoder JA, Cannon JP, Haire RN. Novel Immune-type Receptor Genes and the Origins of Adaptive and Innate Immune Recognition. Integrative and comparative biology. 43(2) : 331-7, 2003.
  • Chen AJ, Zhou G, Juan T, Colicos SM, Cannon JP, Cabriera-Hansen M, Meyer CF, Jurecic R, Copeland NG, Gilbert DJ, Jenkins NA, Fletcher F, Tan TH, Belmont JW. The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway. The Journal of biological chemistry. 277(39) : 36592-601, 2002.
  • Cannon JP, Haire RN, Litman GW. Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate. Nature immunology. 3(12) : 1200-7, 2002.
  • Cannon JP, Colicos SM, Belmont JW. Gene trap screening using negative selection: identification of two tandem, differentially expressed loci with potential hematopoietic function. Developmental genetics. 25(1) : 49-63, 1999.
  • Marini FC, Cannon JP, Belmont JW, Shillitoe EJ, Lapeyre JN. In vivo marking of spontaneous or vaccine-induced fibrosarcomas in the domestic house cat, using an adenoviral vector containing a bifunctional fusion protein, GAL-TEK. Human gene therapy. 6(9) : 1215-23, 1995.
  • Paul JH, Thurmond JM, Frischer ME, Cannon JP. Intergeneric natural plasmid transformation between E. coli and a marine Vibrio species. Molecular ecology. 1(1) : 37-46, 1992.
  • Paul JH, Jeffrey WH, Cannon JP. Production of dissolved DNA, RNA, and protein by microbial populations in a Florida reservoir. Applied and environmental microbiology. 56(10) : 2957-62, 1990.

  • Patents & Licensing
  • Vector system for selection of genes encoding secreted proteins and membrane-bound proteins (University of South Florida - 2006)


  • Profile last modified on 01/14/2013